Midline Abdominal Wall Closure: A New Prophylactic Mesh Concept

Bellón, Juan M.; López-Hervás, P; Rodrı́guez, Marta; García‐Honduvilla, Natalio; Pascual, Gemma; Buján, Julia

doi:10.1016/j.jamcollsurg.2006.06.023

Cited by 36 publications

(29 citation statements)

References 20 publications

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“…The defect area after three weeks ranged from 32.1±5.5 to 35.6±3.1 squared centimeters and was similar to other reports that made only the acute full-thickness defect with areas ranging from 35 to 40 squared centimeters 9,10,18,[30][31][32][33][34][35][36][37][38] . The hypothetic advantage of our model was to simulate the surgical findings in the human hernia repair.…”

Section: Discussionsupporting

confidence: 86%

Animal model of chronic abdominal hernia in rabbit

Silva

Fagundes

Seidel³

et al. 2009

Acta Cir. Bras.

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Purpose: To create a feasible animal model of hernia that should be reliable to test the different types of mesh and/or surgical technique. Methods: Thirty six male New Zealand albino rabbits were submitted to surgical procedure to provoke a standard hole in the abdominal wall. A metallic frame measuring 3 cm length and 1 cm width was allocated longitudinally on the umbilicus scar and the comprehensive three squared centimeters area was resected. A continuous 4.0 polyamide was performed to closure the subcutaneous and skin. Results: During three weeks a score of signals/symptoms was performed to evaluate the wound and clinical conditions. No death or severe complications occurred. In the 3rd week the hernia ring and visceral adhesions were evaluated. Soft omental adherences were present in the hernial sac in all animals. The area of hernia ring ranged from 32.1±5.5 to 35.6±3.1 squared centimeter and the maximum was 39 cm 2 and the minimum was 30 cm 2 . The model results in protrusion which was similar to a human incisional hernia with hernia sac, visceral adhesions and fibrous healing ring. Conclusion: The model was more reliable to test further techniques or mesh on hernia repair. Key words: Hernia, Ventral. Hernia, Abdominal. Wound Healing. Animal Experimentation. Rabbits. RESUMO Objetivo:Criação de um modelo animal de hérnia que seja confiável para testar as diferentes técnicas e tipos de telas. Métodos: Trinta e seis coelhos foram submetidos a procedimento operatório que provocou uma falha na parede abdominal. Uma moldura metálica com 3 cm de comprimento e 1 cm de largura foi colocada longitudinalmente sobre a cicatriz umbilical e ressecada uma área de 3cm 2 . Uma sutura contínua de poliamida 4.0 fechou a tela subcutânea e pele. Resultados: durante três semanas o escore de sinais e sintomas foi coletado para avaliar as condições clínicas e da ferida operatória. Não ocorreram óbitos ou complicações graves. Na terceira semana o anel herniário e aderências peritoneais foram avaliadas. Aderências frouxas estavam presentes no saco herniário em todos os animais. A área do anel herniário variou de 32.1±5.5 a 35.6±3.1 cm 2 , com um máximo de 39 cm 2 e um mínimo de 30 cm 2 . O modelo resultou numa protrusão de vísceras semelhante ao que ocorre em hérnia incisional de humanos. Conclusão: O modelo é factível para testar técnicas operatórias ou telas na reconstrução de hérnias incisionais.

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Section: Discussionsupporting

confidence: 86%

Animal model of chronic abdominal hernia in rabbit

Silva

Fagundes

Seidel³

et al. 2009

Acta Cir. Bras.

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“…In the experimental setting, on using a t-shaped mesh in an animal model, it was also possible to reduce the incidence of incisional hernias [34]. But, once again, the question arises as to how such meshes are to be fixed so that they can assume an effective prophylactic role.…”

Section: Introductionmentioning

confidence: 99%

Primary mesh augmentation with fibrin glue for abdominal wall closure—investigations on a biomechanical model

Schug-Paß

Lippert

Köckerling

2009

Langenbecks Arch Surg

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“…Use of mesh has been shown to decrease the incidence of hernia recurrence [2][3][4]. However, the first generation of polypropylene and polyester meshes contained too much foreign tissue and led to chronic pain and stiffness of the abdominal wall after they had been implanted [5].…”

mentioning

confidence: 99%