Microwave assisted ring-opening of epoxides with N-biaryl sulfonamides in the synthesis of matrix metalloproteinase-9 inhibitors

Microwave-Enhanced Sulphated Zirconia and SZ/MCM-41 Catalyzed Regioselective Synthesis of β-Amino Alcohols Under Solvent-Free Conditions

“…Reactions that typically require high temperatures and extended reaction times have been considerably accelerated using microwave irradiation. The ring-opening of epoxides [ 19 ] can be performed in a very short time under microwave irradiation, compared to the conventional thermal epoxide-opening conditions. The use of microwave irradiation also eliminated the problems of decomposition of the substrates or products during the reaction due to prolonged thermal treatment.…”

Transition metal-free, base mediated one-pot approach for the construction of the benzo[b][1,4,5]oxathiazepine 1-oxide core

“…After two years, the palladium mediated synthesis of bridged eight-membered three-dimensional (3D) aza-heterocyclic sulfoximines was reported by the Chen group (Scheme 1c). 21 On the other hand, epoxide ring opening reactions 22 of various sulfonamides are known to occur via different approaches: (i) under microwave/heating conditions; 23 (ii) transition metal mediated (W, 24 Mo, 25 Gd, 26 Ni, 27 Zr, 28 etc .) reactions and (iii) by the use of chiral Co-salen complexes.…”