Microwave-Assisted Organic Reactions: Eco-friendly Synthesis of Dibenzylidenecyclohexanone Derivatives via Crossed Aldol Condensation

Abstract

Keywords: dibenzylidenecyclohexanone; MAOS; eco-friendly ABSTRAK Telah dilakukan sintesis dibenzilidensikloheksanon dan turunannya melalui reaksi kondensasi aldol silang yang ramah lingkungan menggunakan metode MAOS. Sintesis dibenzilidensikloheksanon (8b) dilakukan melalui reaksi kondensasi antara benzaldehida 4 dan sikloheksanon 2 dalam krus porselen dengan rasio mol 2:1 menggunakan katalis natrium hidroksida selama 2 menit di dalam microwave. Turunan benzaldehida yang digunakan adalah 4-metoksibenzaldehida dan 3,4-dimetoksibenzaldehida untuk mensintesis (2E,6E)-bis(4-metoksibenziliden) siklo heksanon (8a) dan (2E,6E)-bis (3,4-dimetoksibenziliden)sikloheksanon (8c

Energy Savings on Curcumine Derivative Gamavuton-0 Synthesis Using Microwave Irradiation

“…Numbers of researchers have been conducted many synthesis applying microwave irradiation as the energy source. The synthesis of dibenzylidenecyclohexanone derivatives via crossed Aldol-Condensation was successfully conducted using the microwave for more environmentally production [4]. The synthesis of Pyrimidines assisted microwave was also successfully carried out with a good yield [5].…”