Microwave-assisted combustion synthesis of silica-coated Eu:Gd2O3 nanoparticles for MRI and optical imaging of cancer cells

Gayathri, T.; Kumar, R. Arun; Dhilipkumaran, S.; Jayasankar, C.K.; Saravanan, P.; Devanand, B

doi:10.1007/s10854-019-00999-6

Cited by 13 publications

(4 citation statements)

References 25 publications

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“…These observations get along well with the results obtained from XRD analysis. Gayathri et al [24] coated Eu:Gd 2 O 3 NPs with silica and a diffuse ring pattern was obtained which con rmed the amorphous nature of the NPs. Initially, a well-de ned ring structure was obtained in the SAED pattern for the Eu:Gd 2 O 3 NPs.…”

Section: Uv-vis Spectroscopymentioning

confidence: 94%

FericipXT-Coated PEGylated Rutile TiO2 Nanoparticles in Drug Delivery: In-vitro Assessment of Imatinib Release

Bhullar,

Goyal,

Gupta

2023

Preprint

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Study presents a facile synthesis strategy for magnetic field-responsive PEGylated iron-supplement-coated rutile TiO2 nanoparticles (NPs) for stimuli-responsive drug delivery. Imatinib, an anticancer drug, was successfully loaded onto the NPs, and its in-vitro release was investigated under different pH conditions. XRD analysis confirmed the successful synthesis of PEGylated iron supplement-coated rutile titania NPs. HR-TEM studies revealed increased NP size due to coating, PEGylation, and drug-loading. FTIR spectra confirmed the drug loading onto the NPs, while DLS provided hydrodynamic diameter and polydispersity index, indicating appropriate NP synthesis. The PEGylated NPs exhibited negative Zeta Potential, indicating high stability. In-vitro drug-release studies demonstrated controlled release with maximum efficiency under acidic conditions. Hemolysis assay confirmed the safety and biocompatibility of PEGylated NPs. All drug-loaded nanoformulations followed the Peppas-Sahlin model, suggesting Fickian diffusion and Case II relaxation mechanism of drug release. These NPs have potential for targeted delivery and controlled release of chemotherapeutics, minimizing side effects.

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Section: Uv-vis Spectroscopymentioning

confidence: 94%

FericipXT-Coated PEGylated Rutile TiO2 Nanoparticles in Drug Delivery: In-vitro Assessment of Imatinib Release

Bhullar,

Goyal,

Gupta

2023

Preprint

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“…27 These observations get along well with the results obtained from XRD analysis. Gayathri et al 28 coated Eu:Gd 2 O 3 NPs with silica and a diffuse ring pattern was obtained, which conrmed the amorphous nature of the NPs. Initially, a well-dened ring structure was obtained in the SAED pattern for Eu:Gd 2 O 3 NPs.…”

Section: Hr-temmentioning

confidence: 99%

FericipXT-coated PEGylated rutile TiO₂ nanoparticles in drug delivery: in vitro assessment of imatinib release

Bhullar,

Goyal,

Gupta

2024

RSC Adv.

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“…[11] On the one hand, the physical and chemical properties of gadolinium oxide are stable. [12] On the other hand, gadolinium ions can be easily substituted by other rare earth ions to get controllable luminescence. [13] In addition, the phonon energy of gadolinium oxide is low, which contributes to the efficiency of upconversion luminescence.…”

Section: Introductionmentioning

confidence: 99%

Up/down-conversion luminescence of monoclinic Gd₂O₃:Er³⁺ nanoparticles prepared by laser ablation in liquid

Deng

Chen

2022

Chinese Phys. B

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Multifunctional luminescent materials are attracting attention nowadays. In this work, monoclinic Gd2O3:Er3+ nanoparticles, which possess up-conversion luminescence and down-conversion luminescence properties, were successfully synthesized by laser ablation in liquid (LAL) technique. Up-conversion luminescence and down-conversion luminescence of monoclinic Gd2O3:Er3+ nanoparticles were got under the excitation of 980 nm and 379 nm, respectively. In addition, tunable luminescence was got. Furthermore, the cytotoxicity of the nanoparticles is negligible and the fluorescence of the nanoparticles in cell is also strong enough. The results indicate that the Gd2O3:Er3+ nanoparticles synthesized by LAL technique are promising candidates for bio-imaging or other fields that require controllable fluorescence.

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Microwave-assisted combustion synthesis of silica-coated Eu:Gd2O3 nanoparticles for MRI and optical imaging of cancer cells

Cited by 13 publications

References 25 publications

FericipXT-Coated PEGylated Rutile TiO2 Nanoparticles in Drug Delivery: In-vitro Assessment of Imatinib Release

FericipXT-Coated PEGylated Rutile TiO2 Nanoparticles in Drug Delivery: In-vitro Assessment of Imatinib Release

FericipXT-coated PEGylated rutile TiO₂ nanoparticles in drug delivery: in vitro assessment of imatinib release

Up/down-conversion luminescence of monoclinic Gd₂O₃:Er³⁺ nanoparticles prepared by laser ablation in liquid

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Microwave-assisted combustion synthesis of silica-coated Eu:Gd2O3 nanoparticles for MRI and optical imaging of cancer cells

Cited by 13 publications

References 25 publications

FericipXT-Coated PEGylated Rutile TiO2 Nanoparticles in Drug Delivery: In-vitro Assessment of Imatinib Release

FericipXT-Coated PEGylated Rutile TiO2 Nanoparticles in Drug Delivery: In-vitro Assessment of Imatinib Release

FericipXT-coated PEGylated rutile TiO2 nanoparticles in drug delivery: in vitro assessment of imatinib release

Up/down-conversion luminescence of monoclinic Gd2O3:Er3+ nanoparticles prepared by laser ablation in liquid

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FericipXT-coated PEGylated rutile TiO₂ nanoparticles in drug delivery: in vitro assessment of imatinib release

Up/down-conversion luminescence of monoclinic Gd₂O₃:Er³⁺ nanoparticles prepared by laser ablation in liquid