Microscopic inflammatory foci in burn scars: data from a porcine burn model

Wang, Xueqing; Phillips, Gael E.; Wilkie, Ian; Greer, Ristan M.; Kimble, Roy M.

doi:10.1111/j.1600-0560.2009.01376.x

Cited by 6 publications

(2 citation statements)

References 15 publications

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“…Hence, we proposed to call these newly discovered, easily missed LAs ‘keloid‐associated lymphoid tissue’ (KALT). The presence of LAs has previously been reported in other scarring conditions, such as burn scars 68 and Kimura’s disease 69 . In the present study, all the LAs seen expressed VCAM‐1 although some were CD21–, suggesting that these cases represent a relatively early stage of KALT 62 .…”

Section: Discussionsupporting

confidence: 76%

Site-specific immunophenotyping of keloid disease demonstrates immune upregulation and the presence of lymphoid aggregates

Bagabir

Byers

Chaudhry

et al. 2012

British Journal of Dermatology

111

123

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Section: Discussionsupporting

confidence: 76%

Site-specific immunophenotyping of keloid disease demonstrates immune upregulation and the presence of lymphoid aggregates

Bagabir

Byers

Chaudhry

et al. 2012

British Journal of Dermatology

111

123

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“…So, removal of necrotic tissue reduces the inflammation phase and accelerates the wound healing. One of the causes of progressive necrosis is dehydration of the wound due to lack of adequate blood supply (Wang et al, 2010). In this study by considering the amount and type of secretions, no secretions were observed in groups II and V (Table 1).…”

Section: Discussionmentioning

confidence: 66%

Using toasted barley in sesame oil mixture for non-surgical necrosis debridement of experimental burns in rat

Bazzi¹,

Akbarzadeh²,

Obeidi³

et al. 2014

J. Med. Plants Res.

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Burns are the most damaging kind of injuries, major global public health crisis and the fourth most common types of trauma. Decision making in the treatment of burns remains a challenge despite existence of improved assessment techniques and treatment procedures. One of the most complications in healing of burn tissues is necrosis. Several medicinal plants were used to treat skin disorders as burn wounds and necrosis so far. In our traditional medicine, one of the non-surgical methods for debridement of necrotic tissues is using toasted barley in sesame oil. Animal was used, because of the lack of previous scientific research about this herbal mixture for debridement of necrotic tissue. After being anesthetized, the second-degree burns were created in rats. Animals were divided into group I, not treated (control group) and group II treated with fibrinolysin ointment 3% (positive control group). Groups III, IV and V were treated with 1, 3 and 5% w/w doses of toasted barley in sesame oil, respectively. Histopathological and clinical findings showed that treated tissues, especially at dose of 5% w/w were more debrided. Therefore, with respect to our results, this herbal based compound can be used as remedy for debridement of necrotic tissue.

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The correlation of in vivo burn scar contraction with the level of α-smooth muscle actin expression

Wang¹,

Kravchuk²,

Winterford³

et al. 2011

Burns

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Microscopic inflammatory foci in burn scars: data from a porcine burn model

Abstract: This study identifies microscopic inflammatory foci in the porcine scar tissue layer and recommends thorough cleaning/debriding of burned necrotic tissue in order to minimize the formation of these inflammatory foci in scar tissue.

Cited by 6 publications

References 15 publications

Site-specific immunophenotyping of keloid disease demonstrates immune upregulation and the presence of lymphoid aggregates

Site-specific immunophenotyping of keloid disease demonstrates immune upregulation and the presence of lymphoid aggregates

Using toasted barley in sesame oil mixture for non-surgical necrosis debridement of experimental burns in rat

The correlation of in vivo burn scar contraction with the level of α-smooth muscle actin expression

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