Micropatterning of three-dimensional electrospun polyurethane vascular grafts

Effect of immobilized collagen type IV on biological properties of endothelial cells for the enhanced endothelialization of synthetic vascular graft materials

“…In addition, an increment of surface roughness occurred on plasma-oxidized polydimethylsiloxane (PDMS) coated with fibronectin, collagen, and bovine serum albumin, and on poly(acrylonitrile-co-acrylic acid) fibers modified with catalase or collagen [40,41]. Previous reports have suggested that the formation of a confluent monolayer of ECs is not affected by the submicron-micron surface roughness of substrates [42,43]. Based upon these results, the alteration of surface roughness at a magnitude of hundred nanometer reported in this study would not prevent the endothelialization.…”

The Role of Biodegradable Engineered Scaffold in Tissue Engineering

“…They found that grooved patterns induced the uniform alignment of endothelial cell monolayers with morphology similar to naturally aligned endothelium under hemodynamic flow. They also extended these findings by demonstrating that a groove depth or a fiber diameter of about 1 µm can guide the alignment of endothelial cells inside tubular PU grafts (Uttayarat et al, 2010).…”

Biodegradable polymers for dental tissue engineering and regeneration

“…The repeating monomers are flexible and withstand conformational changes [250]. For these characteristics PUR mime body tissues and are extensively used in prostheses like cardiac assist devices [251], small vascular shunts [252], and tracheal tubes [253]. The same properties are available in PUR reinforced carbon fibers [254].…”