Microparticles

Li, Yang; Kohane, Daniel S.

doi:10.1016/b978-0-12-816137-1.00030-1

Cited by 2 publications

(2 citation statements)

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“…Generally, microparticles face limitations due to their size being larger than nanoparticles. Microparticles can penetrate into cells less than NPs so they are used less in biological applications . Biotinylated streptavidin modified PLGA microparticles have shown promising therapeutic effects in the treatment of mammary tumors.…”

Section: Biodegradable Platforms In Vaccine Deliverymentioning

confidence: 99%

“…Microparticles can penetrate into cells less than NPs so they are used less in biological applications. 134 Biotinylated streptavidin modified PLGA microparticles have shown promising therapeutic effects in the treatment of mammary tumors. Biotinylated SA complex increases the immunogenicity of PLGA microparticles.…”

Section: Biodegradable Platforms In Vaccine Deliverymentioning

confidence: 99%

See 1 more Smart Citation

Long-Term Vaccine Delivery and Immunological Responses Using Biodegradable Polymer-Based Carriers

Malek-Khatabi

Tabandeh

Nouri

et al. 2022

ACS Appl. Bio Mater.

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Biodegradable polymers are largely employed in the biomedical field, ranging from tissue regeneration to drug/vaccine delivery. The biodegradable polymers are highly biocompatible and possess negligible toxicity. In addition, biomaterial-based vaccines possess adjuvant properties, thereby enhancing immune responses. This Review introduces the use of different biodegradable polymers and their degradation mechanism. Different kinds of vaccines, as well as the interaction between the carriers with the immune system, then are highlighted. Natural and synthetic biodegradable micro-/nanoplatforms, hydrogels, and scaffolds for local or targeted and controlled vaccine release are subsequently discussed.

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Section: Biodegradable Platforms In Vaccine Deliverymentioning

confidence: 99%

Section: Biodegradable Platforms In Vaccine Deliverymentioning

confidence: 99%