Micrometric Control of the Optics of the Human Eye: Environment or Genes?

Tabernero, Juan; Hervella, Lucía; Benito, Antonio; Colodro‐Conde, Lucía; Ordoñana, Juan R.; Ruiz-Sánchez, Marcos; Marı́n, José Marı́a; Artal, Pablo

doi:10.1167/iovs.16-20957

Cited by 4 publications

(5 citation statements)

References 40 publications

(50 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Hammond et al 12 reported that nearly half of the variance of astigmatism can be explained by genetic reasons. Furthermore, Tabernero et al 13 investigated whether corneal aberrations are genetically or environmentally determined by analyzing 138 eyes of 69 twins. They confirmed that genes play an important role in the variance of corneal aberrations.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Corneal Aberrations in Former Preterm Infants: Results From The Wiesbaden Prematurity Study

Fieß

Schuster

Kölb-Keerl

et al. 2017

Invest. Ophthalmol. Vis. Sci.

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

“…They confirmed that genes play an important role in the variance of corneal aberrations. For instance, the heritability of corneal spherical aberration was reported to be 52%, 13 while a prior Korean population-based study identified 20%. 14 Intraocular pressure is considered as another factor affecting the development of the eye.…”

Section: Discussionmentioning

confidence: 99%

Corneal Aberrations in Former Preterm Infants: Results From The Wiesbaden Prematurity Study

Fieß

Schuster

Kölb-Keerl

et al. 2017

Invest. Ophthalmol. Vis. Sci.

View full text Add to dashboard Cite

show abstract

“…We found a high prevalence of low and moderate myopia in a sample of young twins (average year of birth was 1995.8 ± 3.0). A previous similar study was performed in a sample of twins born in the same geographical area, with an average age at the moment of the measurements (2014) of 54.9 ± 6.3 years (average year of birth was 1958.3 ± 6.7) 34,40 . On average, their manifest refraction gave a SE that was emmetropic (0.0 ± 1.4 D) for the MZ twins, and slightly hyperopic (+0.5 ± 1.6 D) for the DZ twins.…”

Section: Discussionmentioning

confidence: 97%

Inheritance of Refractive Error in Millennials

Pusti

Benito

Madrid‐Valero

et al. 2020

Sci Rep

Self Cite

View full text Add to dashboard Cite

over the last decades, the prevalence of myopia has suddenly increased, and at this rate, half of the world's population will be myopic by the year 2050. Contemporary behavioural and lifestyle circumstances, along with emergent technology, are thought to be responsible for this increase. twin studies mostly reported a high heritability of refractive error across ethnicities. However, heritability is a population statistic and could vary as a result of changing environmental conditions. We studied the variance of refractive error in millennials with 100 twin pairs of university students in southeast Spain. The study population presented a high prevalence of myopia (77%). Statistical analysis showed the variance of refractive error in this group of young twins was mainly driven by the shared environment and, to a lesser extent, by additive genetic factors. We found an increase in myopia prevalence accompanied by a decrease in heritability in this sample of millennials in contrast with results from a previous generation group from the same ethnic origin.

show abstract

“… 35 In a twin study of Tabernero et al. 36 the authors found that genetic factors contribute up to 52% for spherical aberration development. Another important factor for corneal shape development is intraocular pressure.…”

Section: Discussionmentioning

confidence: 99%