“…Microencapsulated drug delivery in aquaculture has so far been accomplished with biopolymers of different origin such as natural gums (Kanazawa 1981), proteins (Petitjean & Csengeri 1995;Yufera, Kolkovski, Fernandez-Diaz, Rinchard, Lee & Dabrowski 2003) and lipids (Lopez-Alvardo, Langdon,Teshima & Kanazawa 1994;Onal & Langdon 2004). However, chitosan has not been evaluated as a wall material so far, despite its favourable characteristics like gelation on contact with counter anions (Bodmeier, Oh & Pramar 1989), formation of ¢lms soluble in acidic pH (Remunan-Lopez & Bodmeier 1996) and its susceptibility to digestive enzymes (Remunan-Lopez, Lorenzo-Lamosa, Vila-Jato & Alonso 1998).…”