Microbial production of natural poly amino acid

Shi, Feng; Xu, Zhinan; Chen, Peilin

doi:10.1007/s11426-007-0061-5

Cited by 25 publications

(20 citation statements)

References 84 publications

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“…ɣ-PGA é um biopolímero aniônico, biodegradável, solúvel em água (Moraes et al, 2013;Yong et al, 2011;Bajaj e Singhal, 2011;Shi et al, 2007;Shi et al, 2006 a, b;Richard e Margaritis, 2003;Goto e Kunioka, 1992). É atóxico para o homem e ambiente (Yong et al, 2011;Bajaj e Singhal, 2011;Richard e Margaritis, 2003;Yoon et al, 2000;Shih e Van, 2001), podendo ser utilizado como espessante, umectante, em industrias de alimentos, cosmético, medicina (Chung et al, 2013;Pereira et al, 2012;Jiang et al, 2011;Hoppensack et al, 2003;Kunioka, 1997;Goto e Kunioka, 1992), farmacêutica (Shi et al, 2007), tratamento de efluentes como agente floculante (Bhunia et al, 2012).…”

Section: Foi Descoberto Por Ivánovics E Colaboradores Em 1937 Como Cáunclassified

“…É atóxico para o homem e ambiente (Yong et al, 2011;Bajaj e Singhal, 2011;Richard e Margaritis, 2003;Yoon et al, 2000;Shih e Van, 2001), podendo ser utilizado como espessante, umectante, em industrias de alimentos, cosmético, medicina (Chung et al, 2013;Pereira et al, 2012;Jiang et al, 2011;Hoppensack et al, 2003;Kunioka, 1997;Goto e Kunioka, 1992), farmacêutica (Shi et al, 2007), tratamento de efluentes como agente floculante (Bhunia et al, 2012). O ɣ-PGA e seus derivados podem ser aplicados como substitutos de hidrogéis e polímeros termoplásticos.…”

Section: Foi Descoberto Por Ivánovics E Colaboradores Em 1937 Como Cáunclassified

“…O ácido gama-poliglutâmico (ɣ-PGA) é um biopolímero composto das formas D-e L-do ácido glutâmico unidas pela ligação amida entre os grupos α-amino e ɣ-carboxílico Shi et al, 2007;Shi et al, 2006 a, b;Ashiuchi e Misono, 2002;Shih e Van, 2001; Kunioka, 1997;Chibnall et al, 1958). (Goto e Kunioka, 1992).…”

Section: Introductionunclassified

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ESTUDO DA COMPOSIÇÃO DO MEIO, EFEITO DA TEMPERATURA E DO pH INICIAL NA PRODUÇÃO DO ÁCIDO ɣ-POLIGLUTÂMICO PELOS MICRO-ORGANISMOS Bacillus subtilis NRRL B - 41094 e Bacillus subtilis NRRL B - 41294

Moraes¹,

Alegre²

2015

Anais Do XX Congresso Brasileiro De Engenharia Química

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Section: Foi Descoberto Por Ivánovics E Colaboradores Em 1937 Como Cáunclassified

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ESTUDO DA COMPOSIÇÃO DO MEIO, EFEITO DA TEMPERATURA E DO pH INICIAL NA PRODUÇÃO DO ÁCIDO ɣ-POLIGLUTÂMICO PELOS MICRO-ORGANISMOS Bacillus subtilis NRRL B - 41094 e Bacillus subtilis NRRL B - 41294

Moraes¹,

Alegre²

2015

Anais Do XX Congresso Brasileiro De Engenharia Química

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“…The productivity can be as high as 100 g/L and the molecular weight is about 1.3 MDa. A pilot-plant test has been successfully performed and a commercial production facility is under construction [50,51].…”

Section: G-polyglutamic Acidmentioning

confidence: 99%

Organic Chemicals from Bioprocesses in China

Huang

Lin

et al. 2010

Biotechnology in China II

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Over the last 20 years, China has successfully established a modern biotechnology industry from almost nothing. Presently, China is a major producer of a vast array of products involving bioprocesses, for some China is even the world's top producer. The ever-increasing list of products includes organic acids, amino acids, antibiotics, solvents, chiral chemicals, biopesticides, and biopolymers. Herein, the research and development of bioprocesses in China will be reviewed briefly. We will concentrate on three categories of products: small molecules produced via fermentation, biopolymers produced via fermentation and small chemicals produced by enzyme-catalyzed reactions. In comparison with the traditional chemical process, in which, nonrenewable mineral resources are generally used, products in the first and second categories noted above can use renewable bioresources as raw materials. The bioprocesses are generally energy saving and environmentally benign. For products developed via the third category, although the raw materials still need to be obtained from mineral resources, the biocatalysts are more effective with higher selectivity and productivity, and the bioprocesses occur under ambient temperature and pressure, therefore, these are "green processes." Most of the products such as citric acid, xanthan and acrylamide etc., discussed in this paper have been in large-scale commercial production in China. Also introduced herein are three scientists, Prof.

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“…Besides, γ-PGA possesses many attractive properties, such as being water soluble, anionic, and edible. Therefore, various applications of γ-PGA have been developed in the fields of medicine, foods, plastics, and even oil or heavy metal ion recovery [1][2][3].…”

Section: Introductionmentioning

confidence: 99%

Effects of Cultivation Conditions on the Production of γ-PGA with Bacillus subtilis ZJU-7

Chen

Shi

Zhang

et al. 2008

Appl Biochem Biotechnol

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Poly-gamma-glutamic acid (gamma-PGA) is a kind of water-soluble and biodegradable polymer made from D- and L-glutamic acid units, which are linked by amide bonds formed between alpha-amino and gamma-carboxylic acid groups. As a potential targeted biopolymer that can be refined from biomass directly, gamma-PGA has been increasingly applied to food, cosmetic, and pharmaceutical industries. In this work, a suitable nitrogen source was screened out for the high and cost-effective production of gamma-PGA in Bacillus subtilis ZJU-7. The effects of inoculation time and initial glucose concentration on the gamma-PGA production were investigated systematically in both shake flasks and a bench-top 15-l fermentor. Under the optimized culture conditions, a high gamma-PGA productivity (46.4 g/l) was obtained after 48 h cultivation at 37 degrees C. Finally, the large-scale fermentation of gamma-PGA production was successfully scaled up to a 100-l fermentor, with the highest gamma-PGA productivity for over 54.0 g/l.

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Microbial production of natural poly amino acid

Cited by 25 publications

References 84 publications

ESTUDO DA COMPOSIÇÃO DO MEIO, EFEITO DA TEMPERATURA E DO pH INICIAL NA PRODUÇÃO DO ÁCIDO ɣ-POLIGLUTÂMICO PELOS MICRO-ORGANISMOS Bacillus subtilis NRRL B - 41094 e Bacillus subtilis NRRL B - 41294

ESTUDO DA COMPOSIÇÃO DO MEIO, EFEITO DA TEMPERATURA E DO pH INICIAL NA PRODUÇÃO DO ÁCIDO ɣ-POLIGLUTÂMICO PELOS MICRO-ORGANISMOS Bacillus subtilis NRRL B - 41094 e Bacillus subtilis NRRL B - 41294

Organic Chemicals from Bioprocesses in China

Effects of Cultivation Conditions on the Production of γ-PGA with Bacillus subtilis ZJU-7

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