Micro-magnetic imprinting of high field gradient magnetic flux sources

Dempsey, Nora; Roy, Damien; Marelli-Mathevon, H.; Shaw, Gorky; Dias, Ana Carolina; Kramer, R. B. G.; Cuong, Le Quoc; Kustov, Mikhail; Zanini, Luiz-Fernando; Villard, Catherine; Hasselbach, K.; Tomba, Caterina; Dumas-Bouchiat, Frédéric

doi:10.1063/1.4886375

Cited by 49 publications

(35 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The currently reachable magnetic gradient (up to 10 6 –10 7 Tm −1 2331) has indirect effects related to the application of HGMGs to cells. First, the effects of magnetic fields with a gradient on the order of 10 6 Tm −1 can manifest itself through the change of the probability of opening/closing mechanosensitive ion channels.…”

Section: Resultsmentioning

confidence: 99%

How a High-Gradient Magnetic Field Could Affect Cell Life

Zablotskii

Polyakova

Lunov

et al. 2016

Sci Rep

167

123

View full text Add to dashboard Cite

The biological effects of high-gradient magnetic fields (HGMFs) have steadily gained the increased attention of researchers from different disciplines, such as cell biology, cell therapy, targeted stem cell delivery and nanomedicine. We present a theoretical framework towards a fundamental understanding of the effects of HGMFs on intracellular processes, highlighting new directions for the study of living cell machinery: changing the probability of ion-channel on/off switching events by membrane magneto-mechanical stress, suppression of cell growth by magnetic pressure, magnetically induced cell division and cell reprograming, and forced migration of membrane receptor proteins. By deriving a generalized form for the Nernst equation, we find that a relatively small magnetic field (approximately 1 T) with a large gradient (up to 1 GT/m) can significantly change the membrane potential of the cell and thus have a significant impact on not only the properties and biological functionality of cells but also cell fate.

show abstract

Section: Resultsmentioning

confidence: 99%

How a High-Gradient Magnetic Field Could Affect Cell Life

Zablotskii

Polyakova

Lunov

et al. 2016

Sci Rep

167

123

View full text Add to dashboard Cite

show abstract

“…Using the magnetic field gradient force, it is possible to organize the magnetic micro-pillars inside PDMS, to favour a particular spatial arrangement 30 . For this purpose, we produced a magnetic template using the approach described above (patterning of a Si substrate using DRIE following by film deposition).…”

Section: Methodsmentioning

confidence: 99%

Magneto-active substrates for local mechanical stimulation of living cells

Bidan

Fratzl

Coullomb

et al. 2017

Preprint

View full text Add to dashboard Cite

show abstract

“…In this line, the magnetic-based technique where magnetically labeled cells can be efficiently captured thanks to the high magnetic field gradients generated by microflux sources is very promising. Its efficacy has been already demonstrated on bacteria [104] and on the mouse embryonic fibroblast cell line NIH/3T3 [105]. This large scale, multiplexed technique that can ultimately be pushed toward a single cell control is intrinsically transposable to other cells, e.g.…”

Section: Active Cell Entrapment and Long Term Soma Positioningmentioning

confidence: 96%