Methods for assessing erythema: a critique of parametric and nonparametric techniques

Doshi, Akash; Zaheer, Ahmed; Stiller, Matthew J.

doi:10.1046/j.1365-4362.1997.00110.x

Cited by 6 publications

(2 citation statements)

References 17 publications

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“…Scores were added at each session for the degree of erythema, edema, pain, and purulent discharge of each anatomic site on a scale from 0 to 3. 28 Nontreating physicians performed scoring evaluations of the modified scale at each study visit, before the laser treatment, and monthly for 2 months after the completion of laser therapy to assess the relative longterm effect of treatment.…”

Section: Methodsmentioning

confidence: 99%

Prospective controlled clinical and histopathologic study of hidradenitis suppurativa treated with the long-pulsed neodymium:yttrium-aluminium-garnet laser

Mahmoud

Tierney

Hexsel

et al. 2010

Journal of the American Academy of Dermatology

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Section: Methodsmentioning

confidence: 99%

Prospective controlled clinical and histopathologic study of hidradenitis suppurativa treated with the long-pulsed neodymium:yttrium-aluminium-garnet laser

Mahmoud

Tierney

Hexsel

et al. 2010

Journal of the American Academy of Dermatology

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“…Over recent years, non-invasive, skin physiological techniques have increased the possibility of objectively measuring erythema, including the erythemal response to UVB. Reflectance spectrophotometry, polarized light photography, colorimetry, spectroradiometry, photoplethysmography and photodensitometry (10)(11)(12) are some of the techniques that make it possible to quantify UV-induced erythema and construct dose-response curves. Laser Doppler flowmetry (LDF) and Laser Doppler Perfusion Imaging (LDPI) have been used in this context and have shown themselves to be valuable tools (9,(13)(14)(15).…”

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confidence: 99%

Phototesting based on a divergent beam – a study on normal subjects

Ilias¹,

Wårdell²,

Falk

et al. 2001

Photoderm Photoimm Photomed

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In a previous publication from our group, phototesting based on a single exposure to a divergent UVB beam with radially decreasing irradiance values was suggested. The aim of the present study was to evaluate technical, practical and biological aspects of the suggested method in normal subjects. Twenty healthy volunteers were provoked on the back with both a collimated beam (four fixed doses, in circular areas with a diameter of 1.5 cm) and the divergent beam (a continuous, radially attenuating dose spectrum covering an area with a diameter of 4.5 cm). Eleven of the subjects were subjected to double provocation with the divergent beam. Assessment was carried out at 6 and 24 h after exposure by measuring the diameter of the reactions both visually and by mapping the skin blood flow change with laser Doppler perfusion imaging (LDPI). Minimal erythemal dose (MED) was determined for both the collimated and the divergent provocation. The reaction diameters were used to decide MED by combination to a mm for mm mapped dose spectrum of the divergent beam profile. Dose-response curves were plotted using the quantitative response data of the LDPI-images against the corresponding dosimetry data. No systematic difference could be proven between LDPI and visual diameters and a 95% confidence interval for the mean difference was calculated to (-0.8, 2.0). Slightly greater diameters were found at the visual assessment performed at 6 h compared to 24 h (95% confidence interval (-0.1, 2.8)). Double provocation showed a good reproducibility both for the visual and the LDPI assessment (P<0.05). The divergent beam provocation allowed a more detailed discrimination of MED compared to the collimated beam provocation. The MED values determined with the divergent beam were, however, generally higher, especially in the lower range of MED values. Technical factors related to the beam divergence and the correct measurement of erythemal effective irradiance are believed to be the explanation for this phenomenon, which is thus correctable. In conclusion, the results from this study support our belief that the phototesting protocol based on a divergent beam constitutes a good opportunity for improved phototesting, since MED and dose-response characteristics may be extracted in more detail from a single UV exposure.

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Psychosensorial assessment of skin damage caused by a sliding on artificial turf: The development and validation of a skin damage area and severity index

Eijnde

Peppelman

Weghuis

et al. 2014

Journal of Science and Medicine in Sport

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Methods for assessing erythema: a critique of parametric and nonparametric techniques

Abstract: 334 Photopiethysmography and laser Doppler flowmetryInstrumental methods for indirectly quantifying erythema include blood plethysmography and blood flow measure-

Cited by 6 publications

References 17 publications

Prospective controlled clinical and histopathologic study of hidradenitis suppurativa treated with the long-pulsed neodymium:yttrium-aluminium-garnet laser

Prospective controlled clinical and histopathologic study of hidradenitis suppurativa treated with the long-pulsed neodymium:yttrium-aluminium-garnet laser

Phototesting based on a divergent beam – a study on normal subjects

Psychosensorial assessment of skin damage caused by a sliding on artificial turf: The development and validation of a skin damage area and severity index

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