Methemoglobinemia Due to Biological Poisoning – Case Report

Abstract

Acquired methemoglobinemia is a dyshaemoglobinemia which results from exposure to various oxidizing agents, results in impaired oxygen delivery to the tissues and can be potentially fatal if untreated. Deliberate ingestion of certain herbicides, insecticides, and pesticides may produce this condition. We report 2 cases of methemoglobinemia due to intentional ingestion of pesticides which were marketed to be safe and contain only biological extracts and fillers. Methylene blue, ascorbic acid, blood transfusion and exchange transfusion are the various modalities of treatment.

Anemia and its Associated Factors Among Women of Reproductive Age in Horticulture Area

“…Anemia is one of the long-term effects of pesticide poisoning (Agustina &Norfai, 2018;Arwin & Suyud, 2016;Azmi et al, 2006;Fauziyyah et al, 2017;Nassar et al, 2016;Neghab et al, 2018;Okvitasari&Anwar, 2017;Patil et al, 2003;Prasetyaningsih et al, 2017;Yushananta et al, 2020). The formation of sulfhemoglobine and methemoglobine compounds in the blood due to pesticide poisoning causes a decrease in hemoglobin levels in red blood cells which results in anemia (Britt &Budinky A, 2000;George et al, 2014;GS Nutakki et al, 2016;G. Nutakki et al, 2017;Pinkhas& All, 1963;Shihana et al, 2016;Sulistyawati et al, 2019).…”

“…In the case of pesticide poisoning, sulfhemoglobine is formed from the sulfur content in pesticides, as well as methemoglobine due to excessive oxidation so that the ferrous compounds turn into ferries. The formation of sulfhemoglobine and methemoglobine will interfere with the function of hemoglobin in delivering oxygen (Britt &Budinky A, 2000;George, Shaikh, Thomas, &Kundavaram, 2014;GS Nutakki, Madhav Makineni, &Madhukiran, 2016;G. Nutakki, Siripurapu, Kumar, &SasiSekhar, 2017;Pinkhas& All, 1963;Shihana, Dawson, & Buckley, 2016).…”