Metastatic Tumors to the Oral Soft Tissues and Jawbones: A Retrospective Analysis of 40 Cases and Review of the Literature

Panoramic radiography and computed tomography of metastatic breast carcinoma in the mandible: Report of a case

“…Nel et al 2 reported that lesions with poorly demarcated margins with cortical destruction, accompanied by clinical signs of swelling, pain, and paraesthesia in the absence of any inflammatory process, should raise suspicion for metastasis. Ho et al 3 showed that the 40 metastatic tumors to the oral soft tissues and jawbones (22 men and 18 women) included 18 cases (45%) involved the gingiva, 16 (40%) the gingiva and jawbones, 5 (12.5%) were exclusively intraosseous, and 1 affected (2.5%) the tongue. Regarding the organ of primary malignancy, the lung was the two most frequent primary site in both men ( n = 6, 27.3%) and women ( n = 5, 27.7%), followed by the colon ( n = 4, 18.2%) and kidney ( n = 3, 13.7%) in men, and colon ( n = 4, 22.2%) and breast ( n = 3, 16.6%) in women.…”

“…Metastasis to the oral soft tissues and jawbones is rare and frequently associated with wide spread disease and dismal prognosis 1–3 . Metastatic lesions to the jaws are known to simulate periodontal and pulpal disease and other radiolucent lesions that can occur in the jaws 4,5 …”

Metastatic colon carcinoma in the maxilla: Highlighting the importance of perioperative oral management: A case report

“…They primarily affect individuals aged 50 -70 years-old, with no significant sex disparity. The mandible and gingiva are the predominant sites for jawbone and soft tissue metastases, respectively; however, the frequency varies depending on the primary lesion (3)(4)(5)(6)(7)(8). In men, oral metastases commonly arise from lung, kidney, liver and prostate cancers, whereas in women, breast, genital and kidney cancers are frequently associated with oral metastases (6).…”