Metástase cutânea rara de provável carcinoma basaloide de cólon simulando granuloma piogênico

Abstract

Acrometastasis is a rare occurrence, especially when affecting the hands. It represents around 0.007-0.2% of all metastatic lesions. The most common site of origin is the lung, accounting for 40-50% of all cases reported in the literature. Kidneys and breasts are other sites also associated with neoplastic lesions that disseminate to the hands. More rarely, the site of origin may be the gastrointestinal tract or other systemic tumors or sarcomas. Early diagnosis is difficult, since the condition may be asymptomatic or may mimic tenosynovitis, arthritis, paronychia, pyogenic granuloma or a local infection. In the present paper, the authors report on a patient with the diagnosis of acrometastasis on both hands originating from a basaloid carcinoma of the anal canal. Response to radiotherapy was poor. Keywords: Colonic neoplasms; Granuloma, pyogenic; Neoplasm metastasisResumo: As acrometástases, principalmente para as mãos, são incomuns e representam cerca de 0,007-0,2% de todas as lesões metastáticas. O pulmão é o sítio de origem mais comum, colaborando com 40-50% dos casos relatados na literatura. Os rins e mamas são outras localizações também relacionadas a neoplasias que metastatizam para as mãos, além de, mais raramente, trato gastrointestinal, outros tumores sistêmicos e sarcomas. Seu diagnóstico precoce é difícil, pois pode ser assintomático, se assemelhar a tenossinovite, artrite, paroníquia, granuloma piogênico ou infecção local. No presente relato, os autores apresentam paciente com diagnóstico de acrometástase, em ambos os quartos quirodáctilos, oriunda de carcinoma basaloide de canal anal, com pobre resposta à radioterapia.

Metástasis falángica en dedo anular derecho en paciente con antecedente de cáncer de colon etapa IV

“…La manifestación clínica habitual comprende aumento de volumen doloroso, generalmente, similar a una infección de partes blandas con eritema, sensibilidad, calor local y limitación de la funcionalidad que puede evolucionar con empeoramiento progresivo de la lesión pudiendo adquirir un aspecto granulomatoso o asociado a ulceración 1,7 . Dada su presentación pueden simular granulomas piogénicos, artritis reumatoide, neoplasia primarias de piel como carcinoma de células escamosas, focos de osteomielitis, tofos gotosos, entre otros; debiendo tener un alto índice de sospecha en pacientes con diagnóstico previo de tumores primarios de otra localización y realizar los estudios pertinentes según sea el caso 7 .…”

Cutaneous metastasis of colon adenocarcinoma: case report and review of the literature

“…1 The most frequent site of cutaneous metastasis of colonic cancer is the abdominal skin, often on surgical incision scars. This is not exclusive to the ad hoc surgical incision scar, but also to preexisting unrelated operative scars.…”

“…8 Uncommon reported sites of skin metastasis of colorectal cancer include scalp, face, eyelids, tip of the nose, nostril, forearm, genitalia, ankle and big toe. 1,2,4,8 Umbilical metastasis (Sister Mary Joseph's nodule) is a recurrent finding. 4,5 …”

“…They typically signify widespread disease with poor prognosis. 1,2 We present a case of an 80-year- old male with a large skin metastatic focus on the lower abdomen about a year after resection of a colonic adenocarcinoma. …”

Most Common Pathway of Metastasis of Rectal Signet Ring Cell Carcinoma to the Skin: Hematogenous

“…Cutaneous metastasis is relatively rare in colorectal cancer (CRC). It has been reported that skin metastasis usually develops within two years after resection of the primary tumor [1][2][3]. Such metastasis indicates advanced stage and associated with poor prognosis due to suboptimal treatment and aggressive biological behavior of tumor.…”