Cutaneous metastasis of colon adenocarcinoma: case report and review of the literature

Abstract

Skin metastases from colorectal carcinoma are rare and signal advanced disease. We present a case of an 80-year-old male with a large skin metastatic focus in the lower abdomen, a year after resection of a colonic adenocarcinoma. The patient had already finished receiving his first cycle of chemotherapy shortly before the discovery of the abdominal nodules and at the same period a chest X-ray, revealed shadows at the base of the right lung.

Lesiones ocupantes de espacio en pared abdominal (no herniaria). La visión del patólogo

“…De hecho, las metástasis son los tumores malignos más frecuentes en pared abdominal. Estas lesiones se pueden subclasificar en tumores metastásicos en pared abdominal (diseminación hematógena o linfática) o infiltración de la pared abdominal (lesiones secundarias), que incluyen las relacionadas con recidivas locales, infiltración por contigüidad e implantes en cicatriz, drenajes y puerto de laparoscopia 12,13,[50][51][52][53][54][55][56] .…”

“…4C y 4D), sarcomas, GIST, melanomas y neoplasias hemolinfopoyéticas pueden ser la causa de metás-tasis o implantes en la pared abdominal [50][51][52][53][54][55][56][57][58][59][60][61][62] . Dentro del grupo de los carcinomas, las metástasis cutáneas, subcutáneas o en tejidos blandos de pared han sido reportadas en pacientes con antecedentes de cáncer de mama, tracto genitourinario, colon, estómago, riñón, carcinoma hepatocelular, vesícula biliar, cáncer ginecológico, esófago, tiroides y pulmón 5,12,13,[50][51][52][53][54][55][56] .…”

“…No es frecuente encontrar metástasis a distancia por carcinomas de vesícula biliar, colorrectal y otros órganos del aparato digestivo en tejido subcutáneo de pared, distantes al sitio de incisión de la laparoscopia [50][51][52][53][54][55][56] .…”

Cutaneous Metastatic Disease: Case Series in a Tropical Setting

“…Cutaneous metastases arising from carcinomas though rare are important findings in clinical practice [1] [2]. It is reported to occur in 0.7% -5% of cancer patients [3], some have reported up to 9% [4], and others 10.4% [5]. In Calabar, the authors setting metastatic skin cancer comprised 6.3% of total histologically diagnosed skin cancer [6].…”

Metastatic Skin Nodules -Is It Pointing Towards Aggressive Tumor Biology?

“…A retrospective study by Looking bill et al showed a median survival of 18 months in patients with the same characteristics. [5] Skin secondaries are reported to be of 0.7% -5% of cancer patients [6] , others have reported to be 9% [7] , Metastatic skin lesions are rare in pediatric age group and it has different distribution in context with age and sex. [3] Metastatic skin lesions are usually discovered on physical examination.…”