Metallkomplexe mit biologisch wichtigen liganden

Synthesis, characterization and cytotoxicity of cyclopentadienyl ruthenium(II) complexes containing carbohydrate-derived ligands

“…The synthesis of ruthenium compounds bearing carbohydrate derived ligands is a relatively unexplored area: our bibliographic search revealed some examples of ruthenium carbonyl clusters containing carbohydrate moieties [30][31][32][33][34], ruthenium-arene complexes containing a carbohydrate phosphite derivative with anticancer properties [35][36][37], and a report of ruthenium cyclopentadienyl complexes with coordinated thiomonosaccharides concerning their promising anti-inflammatory effects [38].…”

Carbohydrate Complexes of Platinum-Group Metals

“…The sodium salt of the acetyl-protected β-D-thioglucopyranose reacts with cationic cyclopentadienylcarbonyl complexes of Fe, Ru, and W (prepared in situ) to give thioglucopyranosato-S complexes 61-63 (Scheme 12). 56 Thermolysis of the iron complex 61 (L ) CO) results in formation of the dinuclear complex 64, which is isomerically pure in solution. The ruthenium complex 62 (L ) PPh 3 ) reacts with CO with substitution of PPh 3 and with CS 2 with insertion yielding complexes 65 and 66, respectively.…”

“…The sodium salt of the acetyl-protected β- d -thioglucopyranose reacts with cationic cyclopentadienyl−carbonyl complexes of Fe, Ru, and W (prepared in situ) to give thioglucopyranosato- S complexes 61 − 63 (Scheme ) . Thermolysis of the iron complex 61 (L = CO) results in formation of the dinuclear complex 64 , which is isomerically pure in solution.…”