Metallkomplexe mit biologisch wichtigen Liganden, XXXIII. Reaktionen von α-Aminosäuren und α-Aminosäurederivaten mit Gold(III)-chlorid/ Metal Complexes with Biological Important Ligands, XXXIII. Reactions of α-Amino Acids and Derivatives there of with Gold(III) Chloride

Abstract

<jats:title>Abstract</jats:title><jats:p>The hydrochlorides of a-aminoacid esters react with Au<jats:sub>2</jats:sub>Cl<jats:sub>6</jats:sub> in thionyl chloride to give the ammonium salts [H<jats:sub>3</jats:sub>NCHRCO<jats:sub>2</jats:sub>R′]+AuCl<jats:sub>4</jats:sub><jats:sup>-</jats:sup> (R = H , Me, R′ = H , Me, Et). The X-ray structure of [H<jats:sub>3</jats:sub>NCH(Me)CO<jats:sub>2</jats:sub>Me]<jats:sup>+</jats:sup>AuCl<jats:sub>4</jats:sub><jats:sup>-</jats:sup> has been determined. The reactions of a-aminoacids with Au<jats:sub>2</jats:sub>Cl<jats:sub>6</jats:sub> in SOCl<jats:sub>2</jats:sub> afford mixtures of ammonium tetrachloroaurate(III) salts with a-amino acids, a-amino acid chlorides or a-amino acid anhydrides as amine components. Cysteine esters reduce gold(III) to give the gold(I) compounds [AuSCH<jats:sub>2</jats:sub>CH(N H<jats:sub>2</jats:sub>)CO<jats:sub>2</jats:sub>R]<jats:sub>n</jats:sub> (R = Me, Et).</jats:p>