Mesenteric extraskeletal osteosarcoma with telangiectatic features: a case report

Lee, Kyung Hwa; Joo, Jae Kyoon; Kim, Dong Yi; Lee, Ji Shin; Choi, Chan; Lee, Jae Hyuk

doi:10.1186/1471-2407-7-82

Cited by 19 publications

(16 citation statements)

References 14 publications

(34 reference statements)

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“…On the other hand, soft-tissue osteoma consists of mature lamellar bone with normal osteocytes and dense connective tissue within the marrow spaces [22]. On imaging, the mineralization of osteosarcoma is usually irregular, poorly circumscribed, and less developed than that of soft-tissue ABC [23]. Microscopic features that support a benign process include bland cytology, low mitotic activity, and lack of necrosis [10].…”

Section: Discussionmentioning

confidence: 99%

Soft-tissue aneurysmal bone cyst with translocation t(17;17)(p13;q21) corresponding to COL1A1 and USP6 loci

Jacquot

Szymańska

Nemana³

et al. 2015

Skeletal Radiol

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We present the case of a 46-year-old woman with no significant past medical history who developed left mid-thigh pain and fullness. Imaging demonstrated a mineralized soft-tissue mass, which increased in size during a year of monitoring, but retained a circumscribed appearance. The mass was located in the medial soft tissues of the thigh, separate from the bone on imaging studies, and this finding was confirmed during excision. The mass showed gross and microscopic features of an aneurysmal bone cyst. This diagnosis was supported by cytogenetic analysis revealing a t(17;17)(p13;q21) translocation corresponding to the USP6 and COL1A1 loci. Soft-tissue aneurysmal bone cyst is a rare entity, with fewer than 25 reports in the literature. Limited cytogenetic information about these tumors is available. To our knowledge, the USP6 and COL1A1 rearrangement has only previously been described in a pediatric soft-tissue aneurysmal bone cyst. We also discuss the differential diagnosis of ossifying soft-tissue lesions.

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Section: Discussionmentioning

confidence: 99%

Soft-tissue aneurysmal bone cyst with translocation t(17;17)(p13;q21) corresponding to COL1A1 and USP6 loci

Jacquot

Szymańska

Nemana³

et al. 2015

Skeletal Radiol

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“…EOS most commonly affects individuals older than 30 and is rarely encountered during the first two decades of life (17). EOS differs from STABC in that it usually has an ill-defined rim on X-rays and is more prone to becoming malignant.…”

Section: Discussionmentioning

confidence: 99%

Soft tissue aneurysmal bone cyst in a 10-year-old girl

et al. 2011

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Abstract. We report the case of a 10-year-old girl with a soft tissue aneurysmal bone cyst (STABC) located in the posterior aspect of the left shoulder. Conventional radiography revealed an oblong mass with a calcified rim. On the computed tomography scan, the lesion appeared to have a non-uniform intralesional density with an incomplete rim. Magnetic resonance imaging revealed a multi-cavity lesion with fluid-fluid levels. Following pathological examination, the lesion was diagnosed as a STABC. This may be only the twentieth reported case in the English literature of this extremely rare benign tumor occurring in soft tissue. Eight months after surgery the patient was assessed at our outpatient clinic and found to have excellent mobility of her left shoulder and no sign of recurrence.

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“…The patient responded well to the treatment, showing no signs of relapse 22. Another case of rare EOS with telangiectatic features occurring in the mesentery has been described by Lee et al24 The patient was a 67-year-old male who presented with blood-tinged stool of 1 month’s duration. Curative resection of the tumor was performed, and the excised tumor showed large multilocular cysts containing old hematomas and necrotic debris.…”

Section: Extraskeletal Tomentioning

confidence: 82%

 Telangiectatic osteosarcoma: a review of literature

Liu¹,

Liu²,

Wang³

et al. 2013

OTT

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Telangiectatic osteosarcoma is a rare variant of osteosarcoma and hence its occurrence, presentation, and prognosis are poorly understood. With advancements in technology and available treatment options, the scenario of its diagnosis, management, and outcome has changed. Chemotherapy with surgery was challenged previously, but has now been proved to be beneficial. We reviewed the available literature and compared results to define the characteristics of the disease, its presentation, radiographic and pathologic features, optimal treatment, and prognosis.

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Mesenteric extraskeletal osteosarcoma with telangiectatic features: a case report

Cited by 19 publications

References 14 publications

Soft-tissue aneurysmal bone cyst with translocation t(17;17)(p13;q21) corresponding to COL1A1 and USP6 loci

Soft-tissue aneurysmal bone cyst with translocation t(17;17)(p13;q21) corresponding to COL1A1 and USP6 loci

Soft tissue aneurysmal bone cyst in a 10-year-old girl

Telangiectatic osteosarcoma: a review of literature

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Mesenteric extraskeletal osteosarcoma with telangiectatic features: a case report

Cited by 19 publications

References 14 publications

Soft-tissue aneurysmal bone cyst with translocation t(17;17)(p13;q21) corresponding to COL1A1 and USP6 loci

Soft-tissue aneurysmal bone cyst with translocation t(17;17)(p13;q21) corresponding to COL1A1 and USP6 loci

Soft tissue aneurysmal bone cyst in a 10-year-old girl

&nbsp;Telangiectatic osteosarcoma: a review of literature

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Telangiectatic osteosarcoma: a review of literature