Mesenchymal stem cells and inorganic bovine bone mineral in sinus augmentation: comparison with augmentation by autologous bone in adult sheep

Gutwald, Ralf; Haberstroh, Jörg; Kuschnierz, Jens; Kister, Carola; Lysek, Dominikus A.; Maglione, Michele; Xavier, Samuel Porfírio; Oshima, Toshiyuki; Schmelzeisen, Rainer; Sauerbier, Sebastian

doi:10.1016/j.bjoms.2009.06.226

Cited by 51 publications

(40 citation statements)

References 19 publications

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“…In the past decade, an increasing number of studies committed to providing novel inorganic biomaterials shows evident of increased interest in implant device [49][50][51]. The biocompatibility, non-cytotoxicity and mechanical properties of zeolite cause it to be appropriately used in the biomedical application as bone graft materials, implant coating, drug carrier and antibacterial agents [52,53].…”

Section: Drug-delivering Biomaterialsmentioning

confidence: 99%

Zeolite-based biomaterials for biomedical application: A review

Purnomo

Setyarini

Sulistyaningsih

2018

AIP Conference Proceedings

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Abstract. This review focuses on the latest reports of the use of zeolites, natural as well as synthetic, as biomedical materials. Discussion on biocompatibility, non-toxicity, zeolite for drug delivery materials, zeolite for bone implants and implant coatings, and the mechanical properties of polymer-zeolite composites are included. The section on the interaction between body tissues and zeolite-based biomaterials focuses on their biocompatibility, non-toxicity, and bioactivity. The next section concerns drug delivering biomaterials. Including delivery of a controlled drug, ionic removal, and synthesized drug delivering materials. The final section concern bone graft substitutes and implant-coating to improve corrosion resistance and osteointegration. The implant material system discussed in a further section is an investigation of the mechanical properties of high-density polyethylene(HDPE)-zeolite composites developed as skull bone implant materials.

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Section: Drug-delivering Biomaterialsmentioning

confidence: 99%

Zeolite-based biomaterials for biomedical application: A review

Purnomo

Setyarini

Sulistyaningsih

2018

AIP Conference Proceedings

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“…[12] Our results correlate with the study of ex vivo cultured and autologous bone marrow derived cell product and showed accelerated bone formation induced by autologous bone marrow cells. [13] The potential of the seeded cells to take host endothelial cells directly affects the vascularization of the scaffold and the mobilization of host progenitor cells toward the graft site. Our results are in conjunction with the review stated that critical-sized bone defects can be repaired by MSC.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of two socket healing procedures with and without mesenchymal stem cells: A comparative study

Jain

Singh

Ganapathy

et al. 2016

Natl J Maxillofac Surg

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Aims and Objectives:Successful preservation of the edentulous ridge after extraction may eliminate or reduce the need for ridge augmentation procedures. It is proved that grafting of fresh extraction sockets with bone grafts promotes ridge preservation. An objective method of maintaining height and width of alveolar ridge using mesenchymal stem cells (MSCs) seeded on collagen membrane was implemented in this study.Methodology:Ten bilaterally symmetrical extraction sockets scheduled for extraction were selected for this study. Involved teeth were extracted atraumatically and the sockets were curetted. MSCs seeded on collagen membrane were placed in the extracted socket on one side. On the other side, only collagen membrane was placed inside the socket. Both the sockets were closed primarily with nonresorbable sutures. Buccolingual and mesiodistal widths of the ridges at three different levels (2 mm below cementoenamel junction [CEJ], 5 mm below CEJ, and 8 mm below CEJ) were assessed immediately after extraction and postoperatively at 3 and 6 months.Results:There was statistically significant observation in maintaining the alveolar ridge width in the grafted site when compared to the nongrafted site.Conclusion:Socket healing procedure using MSCs and collagen membrane was successful in maintaining width of alveolar socket.

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“…In the last few years, the increasing number of papers dedicated to the preparation of new inorganic biomaterials testifies to the growing interest in implant devices [5][6][7]. Although most implant materials are inert, non-immunogenic and non-toxic, devices made of such materials often trigger a variety of adverse reactions, and grafts containing these materials often fail as a result of so-called ''foreign body reactions''.…”

Section: Introductionmentioning

confidence: 99%