Melatoninin Farelerin Bazı Organlarında Alüminyum Birikmesi Üzerine Koruyucu Etkisi

Муселин, Флорин; Dumitrescu, Eugenia; Cristina, Romeo Teodor; Doma, Alexandru; Trif, Alexandra

doi:10.16988/iuvfd.2015.88209

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“…However Melatonin receptor 1A (MTNR1A) is the main receptor mediating melatonin action to modulate GnRH pulsatile activity [6] , therefor it is involved in the regulation of reproductive activity [7] . Futhermore melatonin has a protective effect against aluminum accumulation [8] . Exogenous applications of this hormone during the summer encourage the onset of puberty [3] .…”

Section: Introductionmentioning

confidence: 99%

Kıvırcık Irkı Koyunlarda Melatonin Reseptör 1A (MTNR1A) Geninin MnlI ve RsaI Restriksiyon Enzimleri ile Genetik Varyasyonunun Belirlenmesi

Avanus¹,

Altınel²

2016

Kafkas Univ Vet Fak Derg

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Melatonin receptor 1A (MTNR1A) gene encodes melatonin hormone which regulates the function of seasonal reproductive activity in sheep. The aim of this study was to make the genetic characterization and identify the variant alleles of MTNR1A gene in Kıvırcık breed. Blood samples of 110 Kıvırcık sheep were collected from five different farms located in Kırklareli and Istanbul. DNA extraction was performed from blood samples. Exon 2, the polymorphic region of Melatonin receptor 1A gene, was amplified and PCR products were genotyped by using MnlI and RsaI enzymes.

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Section: Introductionmentioning

confidence: 99%