Medicinal Plants Used in the Treatment and Prevention of Malaria in Cegere Sub-County, Northern Uganda

Anywar, Godwin; Klooster, Charlotte I.E.A. van’t; Boyer, Robert; Wilcox, Merlin; Nalumansi, Patricia A.; Jong, Joop de; Rwaburindori, Protase; Kiremire, Bernard T.

doi:10.17348/era.14.0.505-516

Cited by 29 publications

(31 citation statements)

References 15 publications

(21 reference statements)

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“…Knowledge of traditional medicine and medicinal plants are usually acquired and passed on orally from the elders to the young [34]. This is comparable to reports from other African countries [17,78].…”

Section: Knowledge Dynamics Of Antivenin Plants In Ugandasupporting

confidence: 74%

“…Knowledge is gained through trainings, divine call, and in some instances, the plant to be used can be asked for from the dead [42,59]. Because of civilization, efforts to pass on traditional medical knowledge to children is impeded by lack of interest and the fact that most children spend their youthful years in school [17,34,60]. Most Ugandans know that their current social conditions such as poverty, sleeping in mud houses and activities such as cultivation, hunting, and herding cattle increase their chances of getting bitten by a snake.…”

Section: Knowledge Dynamics Of Antivenin Plants In Ugandamentioning

confidence: 99%

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Antivenin plants used for treatment of snakebites in Uganda: ethnobotanical reports and pharmacological evidences

Omara¹,

Kagoya²,

Openy³

et al. 2020

Trop Med Health

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Snakebite envenomation is a serious public health concern in rural areas of Uganda. Snakebites are poorly documented in Uganda because most occur in rural settings where traditional therapists end up being the first-line defense for treatment. Ethnobotanical surveys in Uganda have reported that some plants are used to antagonize the activity of various snake venoms. This review was sought to identify antivenin plants in Uganda and some pharmacological evidence supporting their use. A literature survey done in multidisciplinary databases revealed that 77 plant species belonging to 65 genera and 42 families are used for the treatment of snakebites in Uganda. The majority of these species belong to family Fabaceae (31%), Euphorbiaceae (14%), Asteraceae (12%), Amaryllidaceae (10%) and Solanaceae (10%). The main growth habit of the species is shrubs (41%), trees (33%) and herbs (18%). Antivenin extracts are usually prepared from roots (54%) and leaves (23%) through decoctions, infusions, powders, and juices, and are administered orally (67%) or applied topically (17%). The most frequently encountered species were Allium cepa, Carica papaya, Securidaca longipedunculata, Harrisonia abyssinica, and Nicotiana tabacum. Species with global reports of tested antivenom activity included Allium cepa, Allium sativum, Basella alba, Capparis tomentosa, Carica papaya, Cassia occidentalis, Jatropa carcus, Vernonia cinereal, Bidens pilosa, Hoslundia opposita, Maytensus senegalensis, Securinega virosa, and Solanum incanum. There is need to identify and evaluate the antivenom compounds in the claimed plants.

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Section: Knowledge Dynamics Of Antivenin Plants In Ugandasupporting

confidence: 74%

Section: Knowledge Dynamics Of Antivenin Plants In Ugandamentioning

confidence: 99%

Antivenin plants used for treatment of snakebites in Uganda: ethnobotanical reports and pharmacological evidences

Omara¹,

Kagoya²,

Openy³

et al. 2020

Trop Med Health

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“…Treatment of cough, diarrhea, snake bite, sterility, pain killer, antidotes, promotes labour, cracks on soles of feet, low immunity, loss of memory, measles, erectile dysfunction [42,43], and fevers [196], leaves used as an antipyretic, for malaria, splenomegaly, and HIV treatment [33,185,197,198]. Fruit used to manage anaemia, worms, asthma, and tonsillitis [199].…”

Section: Growth Habit Parts Used Preparation and Mode Ofmentioning

confidence: 99%

Medicinal Plants Used in Traditional Management of Cancer in Uganda: A Review of Ethnobotanical Surveys, Phytochemistry, and Anticancer Studies

Omara

Kiprop

Ramkat

et al. 2020

Evidence-Based Complementary and Alternative Medicine

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The burden of neoplastic diseases is a significant global health challenge accounting for thousands of deaths. In Uganda, about 32,617 cancer cases were reported in 2018, accompanied by 21,829 deaths. In a view to identify some potential anticancer plant candidates for possible drug development, the current study was designed to compile the inventory of plants with reported anticancer activity used in rural Uganda and the evidences supporting their use in cancer therapy. An electronic survey in multidisciplinary databases revealed that 29 plant species belonging to 28 genera distributed among 24 families have been reported to be used in the management of cancer in Uganda. Anticancer plants were majorly from the families Bignoniaceae (7%), Caricaceae (7%), Fabaceae (7%), Moraceae (7%), and Rutaceae (7%). Most species occur in the wild (52%), though some are cultivated (48%). The growth habit of the plants is as trees (55%) or herbs (45%). Anticancer extracts are usually prepared from leaves (29%), bark (24%), roots (21%), and fruits (13%) through decoctions (53%), as food spices (23%) or pounded to produce ointments that are applied topically (10%). Prunus africana (Hook.f.) Kalkman, Opuntia species, Albizia coriaria (Welw. ex Oliver), Daucus carota L., Cyperus alatus (Nees) F. Muell., Markhamia lutea (Benth.) K. Schum., and Oxalis corniculata L. were the most frequently encountered species. As per global reports, Allium sativum L., Annona muricata L., Carica papaya L., Moringa oleifera Lam., Opuntia species, Prunus africana (Hook.f.) Kalkman, and Catharanthus roseus (L.) G. Don. are the most studied species, with the latter having vincristine and vinblastine anticancer drugs developed from it. Prostate, cervical, breast, and skin cancers are the top traditionally treated malignancies. There is a need to isolate and evaluate the anticancer potential of the bioactive compounds in the unstudied claimed plants, such as Cyperus alatus (Nees) F. Muell., Ficus dawei Hutch., Ficus natalensis Hochst., and Lovoa trichilioides Harms, and elucidate their mechanism of anticancer activity.

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“…On the other hand, the delity levels (FL) where highest for Abuga (Anemia, 60.4%), Alaju (malaria, 57.6%), Amalakwang (poor appetite, 51.8%), Awica (malaria, 44.8%) and Otigo (joint pain and stiffness, 43.8%) ( Table 5). Amaranthus spp is reported to boost blood levels (alleviate anemia) (63); Alaju is reported by Anywar to be an antimalarial agent (34).…”

Section: Discussionmentioning

confidence: 99%

Traditional Medicinal vegetables in Northern Uganda. An ethnobotanical survey.

Nakaziba

Anyolitho

Amanya

et al. 2020

Preprint

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Background A wide range of indigenous vegetables grow in Uganda especially during rainy seasons but scarcely during droughts, except those that are commercially grown. Although a number of these vegetables have medicinal values, they have not been satisfactorily studied besides conservation. Therefore, we conducted an ethnobotanical cross-sectional survey in Northern Uganda in order to document traditional vegetables and their medicinal values. Methods An ethnobotanical survey was conducted in Northern Uganda using both qualitative and quantitative data collection approaches to data collection and analysis. Data was collected using semi-structured, interviewer-administered questionnaires following international ethical codes and key informant interviews using well developed key informant guides. A total of 244 individuals participated in the study. Results The study documented forty five (45) traditional vegetables in Northern Uganda, out of which fifteen (15) also served as folk medicine. These included: Amalakwang (Hibiscus sabdariffa), Akeo (Gynandropsis gynandra), Alaju (Asystasia gangetica), Otigo (Corchorus spp.), Ocwica (Cucubita maxima), and Bojo (Vigna unguiculata) among others. The disease conditions managed using traditional vegetables in the study area included: gastrointestinal, reproductive, musculoskeletal complications as well as non-communicable diseases.Conclusion Northern Uganda has numerous traditional vegetables with medicinal benefits such as gastrointestinal, reproductive and musculoskeletal abnormalities. The community obtains vegetable leaves from the backyard and stews them for the medicinal purposes. However, there was no specific dosage administered. Therefore, we recommend studies to standardize the dosages and verify in laboratory models the efficacy of these vegetables.

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Medicinal Plants Used in the Treatment and Prevention of Malaria in Cegere Sub-County, Northern Uganda

Cited by 29 publications

References 15 publications

Antivenin plants used for treatment of snakebites in Uganda: ethnobotanical reports and pharmacological evidences

Antivenin plants used for treatment of snakebites in Uganda: ethnobotanical reports and pharmacological evidences

Medicinal Plants Used in Traditional Management of Cancer in Uganda: A Review of Ethnobotanical Surveys, Phytochemistry, and Anticancer Studies

Traditional Medicinal vegetables in Northern Uganda. An ethnobotanical survey.

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