Medicinal Plants as a Source of Antioxidants

Levels of two oxidative stress indicators of human sickle erythrocytes incubated in aqueous extracts of Anacardium occidentale, Psidium guajava and Terminalia catappa.

“…Erythrocytes-reduced glutathione is one of the major non-enzymatic endogenous antioxidants protecting tissue against ROS. [9,22] Other antioxidants are alphatocopherol [23,24] , uric acid [25][26][27] , ascorbic acid [28] , carotenoids [29,30] and varieties of plant secondary metabolites such as flavonoid and related polyphenolic compounds. [31,32] Notable erythrocyte enzymatic ROS scavenging systems include glutathione reductase, [17,19] glutathione peroxidase, [33] glucose-6-phosphate dehydrogenase, [18,34] superoxide dismutase, [5,35] catalases, [36][37][38] peroxiredoxins, [39,40] and NADHmethaemoglobin reductase.…”

“…Similarly, scavenging activities for free radicals by natural products of plant origin have been widely reported. [1,28,[45][46][47][48][49] . This study has ascertained the level of oxidative stress by estimating the concentrations of two oxidative stress indicators, namely, MDA and methaemoglobin of sickle erythrocytes incubated in aqueous extracts of three medicinal plants: Anacardium occidentale, Psidium guajava and Terminalia catappa.…”

<i>In vitro</i> anti-inflammatory and free radical scavenging activities of crude saponins extracted from <i>Albuca bracteata</i>Jacq. Bulb.

“…The antioxidant capacity of medicinal plants have been attributed to the presence of alkaloids, polyphenols and saponins (Rao & Gurfinkel, 2000;Sati et al, 2010). Antioxidant property of many medicinal plants are responsible for their therapeutic potentials in the management of degenerative diseases such as diabetes, cancer, inflammation, atherosclerosis (Elekofehinti et al, 2012).…”

Protective Effect of Hydroethanolic Extracts of Solanum scabrum and Cola verticillata Against Cyclophosphamide Induced Toxicity in Female Rats

“…Due to their hydrogen-donating and metal-chelating capacities, these compounds are potential chemopreventive agents (Grzegorczyk, Matkowski, & Wysokinska, 2007). Moreover, some studies have shown that plant base natural products could provide protection against toxicities caused by cyclophosphamide administration (Sati et al, 2010;Nithya, Chandrakumar, & Senthilkumar, 2012).…”

“…Natural products and herbal medicines have been used traditionally for various ailments to avoid side effects due to treatments (Abdel-Hamid, Nazmy, Mahmoud, Fawzy, & Youssof, 2011). Plants produce significant amounts of antioxidants such as polyphenols, phenols and flavonoids (S. C. Sati, N. Sati, Rawat, & O. P. Sati, 2010). Due to their hydrogen-donating and metal-chelating capacities, these compounds are potential chemopreventive agents (Grzegorczyk, Matkowski, & Wysokinska, 2007).…”