Medicinal Herbs Affecting Cancers in Iran and the World

Soltanbeigi, Amir; Dastyar, Neda; Nejad, Fateme Khajoei; Shokri, Samira

doi:10.52547/pbp.4.1.1

Cited by 4 publications

(2 citation statements)

References 6 publications

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“…For this reason ,the reports on the protection against the toxicity of anticancer agents are numerous. In addition, the chief mechanism of the anticancer drugs (including cyclophosphamide) is the oxidative stress [7].…”

Section: Introductionmentioning

confidence: 99%

The role of Selenium in Mitigating The adverse Effect of Cyclophosphamide on The rat Submandibular Salivary Glands

Alnuaimi

Mammdoh

Allaf

2022

Egyptian Journal of Veterinary Sciences

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T HE goal of this study is to see if selenium can counteract the effects of cyclophosphamide on albino rats' submandibular salivary gland tissues. 24 male rats were separated into four groups, each with 6 rats aged 12 -16 weeks weighing 300-400 grams: the first was given physiological saline orally, the second was given selenium (200 mg/kg) orally for 14 days, and the third group was given cyclophosphamide orally once (150 mg /kg). On day 8, group 5 th group(IV) got selenium (200 Mg/kg) and cyclophosphamide (150 mg/kg) intraperitoneally (i.p.). On day 15, all rats were sedated and slaughtered, and the salivary glands of the submandibular region were collected. In comparison to the other groups, the third group lost weight significantly. The histopathological study revealed mucosal acini necrosis with edema surrounding the striated ducts, as well as mucosal acini cell atrophy and vacuoles in the serous acini. A decrease in the number of granulocytic convoluted tubules, an increase in fibrous tissue surrounding the interlobular ducts, and serous acinar apoptosis characteristics were also seen. In comparison to the other groups with moderate to severe foci, immunohistochemical results in this group demonstrated modest to the negative expression of (anti-apoptotic Bcl-2 protein) in stromal cells among the acinar cells of the salivary glands. We concluded that cyclophosphamide caused structural alterations in the submandibular salivary glands of rats and that selenium alleviated these side effects, as seen by histological investigation and immunohistochemistry analysis of Bcl-2 expression.

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Section: Introductionmentioning

confidence: 99%

The role of Selenium in Mitigating The adverse Effect of Cyclophosphamide on The rat Submandibular Salivary Glands

Alnuaimi

Mammdoh

Allaf

2022

Egyptian Journal of Veterinary Sciences

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“…Many medicinal plants contain bioactive and active antioxidant and phenolic compounds, flavonoids, etc., which have medicinal and therapeutic properties (Sytar et al, 2018). Polyphenols are a group of bioactive compounds in plants, of which more than 8,000 species have been identified (Soltanbeigi et al, 2022;Bhuyan et al, 2017;Uroko et al, 2022). Flavonoids are one of the most important categories of polyphenols.…”

Section: Introductionmentioning

confidence: 99%

The Restorative Effect of Titanium Dioxide Nanoparticles Synthesized with Origanum vulgare L., Carvacrol, Hypericum perforatum L., and Hypericin Loaded in Calcium Alginate Scaffold on Staphylococcus aureus-Infected Ulcers in Diabetic Rats

Altememy¹,

Darvishi²,

Shokri³

et al. 2022

AAVS

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In this study, the restorative effect of titanium dioxide nanoparticles (TiO2NPs) synthesized with Origanum vulgare, carvacrol, Hypericum perforatum, and calcium alginate scaffold-loadable calcium alginate on infected wounds with Staphylococcus aureus was investigated in diabetic rats. Eight groups of 12 rats in any group were diabetic by intraperitoneal injection of alloxan. After the rats were anesthetized, 2cm 2 wounds were created and inoculated with bacterial suspension of S. aureus (ATCC 12600) equivalent to the 0.5 MacFarland tube. The hydroalcoholic extracts of Origanum vulgare, Hypericum perforatum, and their active ingredients including carvacrol and hypericin, were prepared, and then TiO2N.Ps. were prepared from them using isopropoxide. The antibiotic methicillin and calcium alginate pad was also loaded as control of nanoparticles embedded in the calcium alginate pad and then the restorative effect on the wound was studied. On days 0, 3, 7, 14, and 21, hematoxylin-eosin slides (H&E) of the tissue, angiogenesis rate, and division of fibroblast cells and Masson's trichrome slides were used to determine the rate of collagenization, wound, and extracellular matrix. After the treatment, the size of the wound in the Tio2 N.P. synthesis by Origanum vulgare, Tio2 N.P. synthesis by carvacrol, methicillin, Tio2 N.P., and alginate pad groups of diabetic rats and alginate pad group of non-diabetic rats were determined 7.03

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Investigating the factors affecting self-care behaviors in diabetic patients: A systematic review

et al. 2022

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Diabetes is one of the most common non-communicable diseases that have far-reaching economic and social consequences and threaten the national production and economy of countries. However, diabetes is a disease of self-control. Therefore, self-care strategies can maintain patients' independence while reducing the burden imposed on health care resources. This study aimed to investigate the factors affecting self-care behaviors in diabetic patients. This study is a systematic review; Google Scholar, SID, Scopus, PubMed, Science Direct, and ISI databases were used; 17,500 articles were found including the keywords "self-care", "diabetes" and "affecting factors" in the search process and all studies after 2010 were included. After reviewing the titles and abstracts, 51 studies were included. The studies' reports on self-care behaviors and their prevalence were very different depending on the tools used . The studies show the relationship between various factors including demographic, socio-economic, and psychological with self-care behaviors in patients with diabetes, which the most important variables included educational status, age, gender, marital status, BMI, occupational status, duration of illness, comorbidities, income, having glucometer, perceived severity of the disease and its complications, perceived barriers, diabetes distress, diabetes knowledge, perceived susceptibility, self-efficacy, social and family support, depression, anxiety. Due to the relationship of demographic, socio-economic, and psychological factors with self-care behaviors in patients with diabetes, it is suggested that a comprehensive program for the management of caring behaviors in diabetic patients should be designed to include all of the above.

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Medicinal Herbs Affecting Cancers in Iran and the World

Cited by 4 publications

References 6 publications

The role of Selenium in Mitigating The adverse Effect of Cyclophosphamide on The rat Submandibular Salivary Glands

The role of Selenium in Mitigating The adverse Effect of Cyclophosphamide on The rat Submandibular Salivary Glands

The Restorative Effect of Titanium Dioxide Nanoparticles Synthesized with Origanum vulgare L., Carvacrol, Hypericum perforatum L., and Hypericin Loaded in Calcium Alginate Scaffold on Staphylococcus aureus-Infected Ulcers in Diabetic Rats

Investigating the factors affecting self-care behaviors in diabetic patients: A systematic review

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