Medical Marijuana and Chronic Pain: a Review of Basic Science and Clinical Evidence

Jensen, Bjørn Gotlieb; Chen, Jeffrey; Furnish, Timothy; Wallace, Mark

doi:10.1007/s11916-015-0524-x

Cited by 104 publications

(74 citation statements)

References 74 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It is a so-called "whole plant" extract, includes THC and CBD at a ratio of 1:1. It stems directly from the cannabis plant and is not synthetic, yet it undergoes an extensive processing regimen [15]. THC and CBD represent approximately 70 percent of the product, with 5 percent from other cannabinoids and the remainder being terpenoids, flavonoids, sterols, alkanes, and other chemicals [15].…”

Section: Semi-synthetic Formsmentioning

confidence: 99%

Pharmacology of Marijuana

Oberbarnscheidt¹,

Miller²

2017

J Addict Res Ther

View full text Add to dashboard Cite

show abstract

Section: Semi-synthetic Formsmentioning

confidence: 99%

Pharmacology of Marijuana

Oberbarnscheidt¹,

Miller²

2017

J Addict Res Ther

View full text Add to dashboard Cite

show abstract

“…Cannabis or medical marijuana is related to the use of cannabis and isolated cannabinoids to cure diseases and relieve pain [28]. In addition, cannabis and its compounds are used to treat chronic pain.…”

Section: Cannabis and Cannabinoids As Analgesicmentioning

confidence: 99%

Analgesic Potential of Extracts and Derived Natural Products from Medicinal Plants

Rauf¹,

Jehan²,

Ahmad³

et al. 2017

Pain Relief - From Analgesics to Alternative Therapies

View full text Add to dashboard Cite

Since ancient times, plants have always been a reliable and important source of bioactive compounds used to treat several diseases, and thus play a central role in human health. In addition, medicinal plants are a rich source of bioactive secondary metabolites that have a wide range of medicinal uses. This is the reason why, currently, 90% of drugs come from natural or semisynthetic origins. Chemical diversity of plants made them one of the main sources for the extraction and purification of secondary metabolites. On the other hand, pain has always been a cause of concern to humans who searched for a remedy from natural sources, mostly from plants. In this respect, substances that relieve pain (algesia) can be described as analgesics (painkillers). Chemically diverse structures have been identified as pain relievers; they relieve pain through various mechanisms and act either centrally (opioids receptor agonism) or peripherally. Therefore, this chapter is intended to summarize the literature pertaining to plants and their constituents discovered with analgesic potential in the last four decades.

show abstract

“…Though currently limited worldwide production is limited to 65 thousand hectares, cultivation of Cannabis sativa for fiber plus hempseed purposes combined grew by 38% between 2010 and 2012 [2]. There is growing interest in medicinal uses of non-psychoactive hemp extracts like cannabidiol (CBD) to reduce pain [3], severity of epileptic seizures [4,5], and anxiety [6]. These medicinal prescriptive uses in conjunction the expansion of indoor Cannabis propagation for psychoactive THC properties have stimulated the expansion of large indoor grow operations in several markets.…”

Section: Introductionmentioning

confidence: 99%