Mechanoresponsive polymer nanoparticles, nanofibers and coatings as drug carriers and components of microfluidic devices

Biomolecular Release from Alginate‐modified Electrode Triggered by Chemical Inputs Processed through a Biocatalytic Cascade – Integration of Biomolecular Computing and Actuation

“…Release processes from various micro/nano‐porous materials and polymer matrices have been demonstrated. Different signal‐responsive materials, particularly those sensitive to pH and temperature variation , as well as application of external magnetic field or electrical potentials at conducting interfaces have been used to activate the release processes. Among many other materials, alginate hydrogels attracted special interest because of their possible use as matrices for entrapment and controlled release of biomolecular species, including drugs .…”

Synthesis of naringin‐based polymer brushes via seATRP

“…It is expected that these synthesized thermos‐responsive amphiphilic copolymer brushes can become key elements of microfluidics devices and drug delivery systems. Their thermo‐mechanical response involves a reversible wettability change from hydrophilic to hydrophobic, as well as a reversible swelling/shrinkage transition when they are in contact with water and temperature crosses their lower critical solution temperature (LCST) . One of the applications of such polymer materials in the framework of microfluidics and filtration can be membranes and microchannels with regulated on‐demand flow rate .…”

“…[83][84][85] One of the applications of such polymer materials in the framework of microfluidics and filtration can be membranes and microchannels with regulated on-demand flow rate. 85 Another application might involve water filters with self-cleaning triggered by the temperature variation through their LCST, when the filter fibers swell and shake loose deposits, 85 which can be potentially used in such technologies as cell harvesting and formation of biologically active thin films in tissue engineering. In this layout, PMMA is perhaps the most industrially important biocompatible polymer, which possesses high molecular weight (MW), insolubility in water, tolerance to enzymatic attack, and excellent optical qualities.…”

“…Their thermo‐mechanical response involves a reversible wettability change from hydrophilic to hydrophobic, as well as a reversible swelling/shrinkage transition when they are in contact with water and temperature crosses their lower critical solution temperature (LCST) . One of the applications of such polymer materials in the framework of microfluidics and filtration can be membranes and microchannels with regulated on‐demand flow rate . Another application might involve water filters with self‐cleaning triggered by the temperature variation through their LCST, when the filter fibers swell and shake loose deposits, which can be potentially used in such technologies as cell harvesting and formation of biologically active thin films in tissue engineering.…”

Tuning thermoresponsive behavior of diblock copolymers and their gold core hybrids

“…They have potential applications in areas such as drug delivery [2,3] and other biomaterials [4], microfluidics [5][6][7], and catalysts [8,9]. The most widely studied systems are thermoresponsive materials that exhibit a cloud point (CP, the estimation of lower critical solution temperature, LCST) in response to environmental heat.…”