Mechanisms of Calcification in Atherosclerosis

Anderson, H. Clarke; McGregor, Douglas H.; Tanimura, Akira

doi:10.1007/978-1-4612-3326-8_15

Cited by 5 publications

(2 citation statements)

References 37 publications

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“…31 Ross and Glomset 32 classify calcifications as complicated lesions, the final stage of atherosclerotic disease. Thus, nonmineralized atheromas are most likely an earlier manifestation of atherosclerosis than mineralizations.…”

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confidence: 99%

Ultrasonographic manifestations of common carotid atherosclerosis in elderly eastern Finnish men. Prevalence and associations with cardiovascular diseases and risk factors.

Salonen

Tervahauta

Salonen

et al. 1994

Arterioscler Thromb

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We investigated the prevalence and associations with cardiovascular symptoms, signs, and risk factors of common carotid atherosclerosis using B-mode ultrasonography in a population sample of 182 eastern Finnish men aged 70 to 89 years. Men were examined in 1989 as a part of the 30-year follow-up examination of the eastern Finnish cohort of the Seven Countries Study. The mean maximal intima-media thickness (IMT) of the right and left common carotid arteries was 1.5 mm (range, 0.7 to 5.3 mm; standard deviation, 0.7 mm). Fifty-one percent of the subjects had nonmineralized atheroma and 91% had single or multiple mineralizations in any of the arterial segments imaged. Both mean maximal IMT and nonmineralized atheromas were associated significantly (P<.05) with the presence of cerebral atherosclerosis, carotid C ardiovascular diseases are very common in Finland, especially in middle-aged men. 1 The majority of cardiovascular diseases are of atherosclerotic origin. The occurrence of human atherosclerosis has traditionally been studied on the basis of either autopsies or invasive angiography. Therefore, it has not been possible to carry out studies in randomly selected population samples. High-resolution ultrasonography enables the noninvasive imaging and quantitative assessment of both early and advanced atherosclerotic lesions in superficial large and medium-sized arteries.Ultrasonographic assessment of atherosclerosis has been applied in population samples in studies of occurrence and risk factors of early atherosclerosis. 211 The prevalence of asymptomatic carotid atherosclerosis in elderly populations is, however, not well known. -10Ultrasonographically assessed carotid atherosclerosis has predicted the risk of coronary events in middle-aged men. and symptoms of coronary heart disease (CHD) and cerebrovascular disease in the elderly.12 Prospective population studies indicate that the impact of the major coronary risk factors, smoking, elevated serum cholesterol concentration, and hypertension, is attenuated in the elderly. 13 There are no previous reports from prospective studies on the association of risk factors assessed in middle age and later in life with the occurrence of carotid atherosclerosis in old age.The purpose of the present study was to investigate the prevalence of different manifestations of B-mode ultrasonographically assessed cases of common carotid atherosclerosis and their associations with cardiovascular symptoms and signs assessed at the same time and with past and present levels of the major cardiovascular risk factors in elderly eastern Finnish men. Methods Study PopulationIn 1959, all 1711 men aged 40 to 59 years, living in two rural areas in eastern and southwestern Finland, were invited to take part in a prospective study of CHD and other atherosclerotic diseases, the Seven Countries Study. 1415 In this original study cohort 823 men were from eastern Finland and 888 men were from southwestern Finland. The 30-year follow-up examination of surviving men was performed in 1989, wh...

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confidence: 99%

Ultrasonographic manifestations of common carotid atherosclerosis in elderly eastern Finnish men. Prevalence and associations with cardiovascular diseases and risk factors.

Salonen

Tervahauta

Salonen

et al. 1994

Arterioscler Thromb

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“…Od tada su brojne kliničke, laboratorijske i epidemiološke studije u svijetu ispitivale učinke pušenja na zdravlje i potvrdile da konzumiranje duvana i duvanskih proizvoda i to posebno pušenje cigareta, ali i izloženost duvanskom dimu, odnosno tzv. pasivno pušenje, znatno doprinose obolijevanju i prijevremenom umiranju od niza bolesti (3)(4)(5).…”

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Pušenje kao faktor rizika za nastanak kardiovaskularnih bolesti kod zdravstvenih i prosvetnih radnika Crne Gore

Magdelinić¹,

Živanović²,

Babović³

et al. 2018

Sestrinska reč

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¹Visoka medicinska škola Berane,²Srednjoškolski centar Foča, ³Klinički centar Crne Gore, ⁴Medicinski fakultet Podgorica, ⁵Medicinski fakultet Podgorica APSTRAKT UVOD: Godišnje više ljudi umre od kardiovaskularnih bolesti (KVB) nego od bilo kog drugog uzroka. Faktori rizika u nastanku KVB su mnogobrojni i imaju kumulirajući efekat.Rezultati dosadašnjih studija pokazuju da pušenje cigareta ima ključnu ulogu u razvoju KVB. CILJ ISTRAŽIVANJA: Utvrditi uticaj pušenja, kod zdravstvenih i prosvjetnih radnika, na nastanak kardiovaskularnih bolesti. Ispitanici i metode istraživanja: Istrživanje je sprovedeno po tipu studije presjeka u populaciji zdravstvenih i prosvjetnih radnika opštine Berane. Uzorak je bio sastavljen od 109 zdravstvenih radnika i 71 prosvjetnih radnika. U istraživanju su učestvovali svi zdravstveni radnici zaposleni u Domu zdravlja ,,Dr Nika Labović"u Beranama i svi zaposleni prosvjetni radnici zaposleni u Osnovnoj školi ,,Vuk Kardžić" u Beranama. U istraživanju je korištena anketa, a podaci su prikupljeni prospektivno. Kao instrumenti za sprovođenje istraživanja upotrijebili su se upitnici: "Work related stress" i "Cindi". Za statističku obradu podataka korišćeni su X kvadrat i ANOVA test. REZULTATI ISTRAŽIVANJA: Prosječna starosna dob zdravstvenih radnika je iznosila 43.70±11.90 godina, dok je prosječna starosna dob prosvjetnih radnika 42.29±10.90 godina. Više od polovine zdravstvenih i prosvjetnih radnika se izjasnilo da su pušili. Svakodnevno je pušilo 36.7% zdravstvenih radnika i 39.4% prosvjetnih radnika. U grupi prosvjetnih radnika najveci procenat ispitanika (49.3%) skoro nikada nije izložen duvanskom dimu na radnom mjestuU odnosu na zdravstvene radnike, prosvjetni radnici su značajno zabrinutiji zbog zdravstvenih posljedica pušenja. ZAKLJUČAK: Kod zdravstvenih i prosvjetnih radnika opštine Berane pušenje je značajan faktor rizika za razvoj kardiovaskularnih bolesti. KLJUČNE RIJEČI: kardiovaskularne bolesti, faktori rizika, pušenje.

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Stoffwechselkrankheiten

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Gelenkpathologie

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Mechanisms of Calcification in Atherosclerosis

Cited by 5 publications

References 37 publications

Ultrasonographic manifestations of common carotid atherosclerosis in elderly eastern Finnish men. Prevalence and associations with cardiovascular diseases and risk factors.

Ultrasonographic manifestations of common carotid atherosclerosis in elderly eastern Finnish men. Prevalence and associations with cardiovascular diseases and risk factors.

Pušenje kao faktor rizika za nastanak kardiovaskularnih bolesti kod zdravstvenih i prosvetnih radnika Crne Gore

Stoffwechselkrankheiten

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