Mechanical characterization and ion release of bioactive dental composites containing calcium phosphate particles

Natale, Livia C.; Rodrigues, Marcela Charantola; Alania, Yvette; Chiari, Marina D.S.; Boaro, Letícia Cristina Cidreira; Cotrim, Marycel E.B.; Vega, O.; Braga, Roberto Ruggiero

doi:10.1016/j.jmbbm.2018.05.022

Cited by 32 publications

(22 citation statements)

References 41 publications

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“…A possible way to promote tooth remineralization reduce development of secondary caries, remineralize the hybrid layer, prevent enzymatic and hydrolytic degradation of the bonded interface has been the incorporation of calcium orthophosphates and bioactive glass particles in resin-based materials [ 82 , 83 , 84 , 85 , 86 , 87 , 88 ]. In this way, the materials behave as ions source, which would release calcium and phosphate to the liquid medium and thus create a supersaturated environment, which in turn would favor mineral deposition on the restoration/tooth interface [ 87 ].…”

Section: Discussionmentioning

confidence: 99%

Cytotoxic Evaluation and Determination of Organic and Inorganic Eluates from Restorative Materials

et al. 2021

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Over the last years, diverse commercial resin-based composites have dominated as dental filling materials. The purpose of the present study was to determine organic and inorganic eluates from five restorative materials using GC/MS and ICP–OES and to compare the effect on cell survival of human gingival fibroblasts of a conventional and a bioactive resin. Five commercially available restorative materials were employed for this study: ActivaTM Bioactive Restorative, ENA HRi, Enamel plus HRi Biofunction, Fuji II LC Capsule, and Fuji IX Capsule. Disks that were polymerized with a curing LED light or left to set were immersed in: 1mL methanol or artificial saliva for GC/MS analysis, 5mL deionized water for ICP–OES, and 5mL of culture medium for cell viability. Cell viability was investigated with a modified staining sulforhodamine B assay.The following organic substances were detected: ACP, BHT, BPA, 1,4-BDDMA, CQ, DBP, DMABEE, HEMA, MCE, MeHQ, MOPA, MS, TMPTMA, and TPSb and the ions silicon, aluminum, calcium, sodium, and barium. Activa Bioactive Restorative was found to be biocompatible. Elution of organic substances depended on material’s composition, the nature of the solvent and the storage time. Ions’ release depended on material’s composition and storage time. The newly introduced bioactive restorative was found to be more biocompatible.

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Section: Discussionmentioning

confidence: 99%

Cytotoxic Evaluation and Determination of Organic and Inorganic Eluates from Restorative Materials

et al. 2021

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“…17 In addition, up to a 40% increase in fracture strength values is observed when resinous materials containing functionalized DCPD particles were compared to materials with nonfunctionalized particles. 6,13,18 DCPD functionalization after complete precipitation of particles has not been evaluated.…”

Section: Introductionmentioning

confidence: 99%

Mechanical properties and surface roughness of polymer-based materials containing DCPD particles

et al. 2020

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The purpose of this study was to synthesize dicalcium phosphate dihydrate (DCPD) particles functionalized with triethylene glycol dimethacrylate (TEGDMA) through different routes by varying the receptor solution: ammonium phosphate (AP groups) or calcium nitrate (CN groups) and the moment in which TEGDMA was incorporated: ab initio (ab) or at the end of dripping the solution (ap). Two syntheses were performed without adding TEGDMA (nf). The particles were characterized by X-ray diffractometry, true density (using a helium pycnometer), surface area, and scanning electron microscopy. A 20 vol% of DCPD particles from the D, E, and F groups was added to the resin matrix to determine the degree of conversion (DC), biaxial flexural strength (BFS), the flexural modulus (FM), and surface roughness after an abrasive challenge (RA). A group with silanized barium glass particles was tested as a control. The data were submitted to ANOVA/Tukey's test (DC, BFS, and RA), and the Kruskal-Wallis test (FM) (alpha = 0.05). BFS values varied between 83 and 142 MPa, and the CN_ab group presented a similar value (123 MPa) to the control group. FM values varied between 3.6 and 8.7 GPa (CN_ab and CN_nf groups, respectively), with a significant difference found only between these groups. RA did not result in significant differences. The use of calcium nitrate solution as a receptor, together with ab initio functionalization formed particles with larger surface areas. Higher BFS values were observed for the material containing DCPD particles with a higher surface area. In general, the DC, FM, and RA values were not affected by the variables studied.

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“…One possible approach to reduce the risk of secondary caries development is to add bioactive agents that promote remineralization of tooth structure through calcium and phosphate ion release. In this regard, a wide range of calcium phosphates (CaP) such as hydroxyapatite (HAp), amorphous calcium phosphate (ACP), tetracalcium phosphate (TTCP) and mono-and dicalcium phosphates (MCPM and DCPA) have been studied as fillers in dental composites [7][8][9][10][11][12][13][14][15][16][17][18]. Nanostructured calcium-hydroxyapatite (HAp) presents as a desired component in dental materials due to its biocompatibility, bioactivity and chemical similarity to inorganic component of the teeth [19].…”

Section: Introductionmentioning

confidence: 99%

The effect of calcinated hydroxyapatite and magnesium doped hydroxyapatite as fillers on the mechanical properties of a model BisGMA/TEGDMA dental composite initially and after aging

et al. 2018

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The aim of this study was to investigate the possibility of modifying model BisGMA/TEGDMA dental composite by substituting 10 wt. % of conventional glass fillers with bioactive fillers based on calcinated nanosized hydroxyapatite (HAp) and Mg doped hydroxyapatite (Mg-HAp). HAp and Mg-HAp powders were synthesized hydrothermally. Mechanical properties: hardness by Vickers (HV) and flexural strength (Fs) were tested initially and after being stored for 28 days in simulated body fluid (SBF). The experimental composites with HAp and Mg-HAp particles showed no statistically significant difference in HV compared to the control (p>0.05) either initially or after storage. Although mean Fs values of modified composites tested initially were lower (62 MPa) than those of the control (72 MPa), after 28 days of storage in SBF Fs values were greater for modified composites (42 MPa control sample, 48 MPa HAp and Mg-HAp samples). In vitro bioactivity of BisGMA/TEGDMA composites with HAp and Mg-HAp particles after 28 days in SBF was not detected. Keywords: hydroxyapatite; magnesium; dental composite; mechanical properties;

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Mechanical characterization and ion release of bioactive dental composites containing calcium phosphate particles

Cited by 32 publications

References 41 publications

Cytotoxic Evaluation and Determination of Organic and Inorganic Eluates from Restorative Materials

Cytotoxic Evaluation and Determination of Organic and Inorganic Eluates from Restorative Materials

Mechanical properties and surface roughness of polymer-based materials containing DCPD particles

The effect of calcinated hydroxyapatite and magnesium doped hydroxyapatite as fillers on the mechanical properties of a model BisGMA/TEGDMA dental composite initially and after aging

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