Precision data are presented for the break-up reaction, 2 H( p, pp)n, within the framework of nuclear-force studies. The experiment was carried out at KVI using a polarized-proton beam of 190 MeV impinging on a liquid-deuterium target and by exploiting the detector, BINA. Some of the vector-analyzing powers are presented and compared with state-of-the-art Faddeev calculations including three-nucleon forces effect. Significant discrepancies between the data and theoretical predictions were observed for kinematical configurations which correspond to the 2 H( p, 2 He)n channel. These results are compared to the 2 H( p, d)p reaction to test the isospin sensitivity of the present three-nucleon force models. The current modeling of two and three-nucleon forces is not sufficient to describe consistently polarization data for both isospin states. Understanding the exact nature of the nuclear force is one of the long-standing questions in nuclear physics. In 1935, Yukawa successfully described the pair-wise nucleon-nucleon (NN) interaction as an exchange of a boson [1]. Current NN models are mainly based on Yukawa's idea and provide an excellent description of the high-quality database of proton-proton and neutron-proton scattering [2] and of the properties of the deuteron. However, for the simplest three-nucleon system, triton, three-body calculations employing NN forces clearly underestimate the experimental binding energies [3], demonstrating that NN forces are not sufficient to describe the three-nucleon system accurately. Some of the discrepancies between experimental data and calculations solely based on the NN interaction can be resolved by introducing an additional three-nucleon force (3NF). Most of the current models for the 3NF are based on a refined version of Fujita-Miyazawa's 3NF model [4], in which a 2π-exchange mechanism is incorporated by an intermediate ∆ excitation of one of the nucleons [5,6].The structure of the 3NF can be studied via a measurement of observables in three-nucleon scattering processes. More detailed information on the spin dependence of the 3NF can be obtained by measuring polarization observables such as the analyzing powers. For this, a series of * Electronic address: messchendorp@kvi.nl extensive studies of 3NF effects in elastic-scattering reactions have been performed at KVI and other laboratories. Precision measurements of the vector analyzing power of the proton in elastic proton-deuteron scattering have been performed at various beam energies ranging from 90 to 250 MeV [7,8,9,10,11]. Also, vector and tensor analyzing powers in elastic deuteron-proton scattering have been obtained at various beam energies ranging from 75 to 270 MeV [12,13,14,15,16,17]. In these measurements, systematic discrepancies between data and theoretical predictions which rigorously solve the Faddeev equations and using only NN potentials were observed. A large part of the discrepancies were removed by adding a 3NF to the NN potentials. Nevertheless, there are still unresolved problems specially at higher...