Measurement of pyuria in urinary tract infections.

Houston, I. B.

doi:10.1136/adc.44.236.480

Cited by 11 publications

(5 citation statements)

References 17 publications

(18 reference statements)

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“…Finally, the limitation of pyuria should be factored into final outcome of the test, considering the present study and other referenced studies. Method of urine collection, transportation , storage, degree of precision in the interpretation of either spun or unspun urine specimen (13,19,43,44,45) are some key factors that needs to be appropriately considered before pyuria become more useful in the diagnoses of UTI.…”

Section: Discussionmentioning

confidence: 99%

Significance of Pyuria in the Diagnosis of Urinary Tract Infection in Children with Sickle Cell Anaemia in Maiduguri, Nigeria

Mava¹,

Timothy²,

Zailani³

et al. 2012

Af J Clin Exp Micro

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Urinary tract infection (UTI) is a significant cause of morbidity and mortality in children, especially in those with sickle cell disease, who are at higher risk of infections. It will be useful to have a simple test which can be used in resource limited health facilities as a means of screening such children for UTI with the view to instituting prompt treatment. This study is carried out to determine the usefulness of significant pyuria in detecting UTI in febrile children with sickle cell anaemia (SCA). Two hundred and fifty febrile children with sickle cell anaemia that attended State Specialist Hospital and University of Maiduguri Teaching Hospital (UMTH) were prospectively studied with their consent. Urine sample was collected using standard procedure, examined for pus cells and was cultured at the Microbiology laboratory of UMTH. The study showed UTI prevalence of 26%. Significant pyuria was found to have sensitivity of 55.4%, specificity of 77.8%, the efficacy of the test was 72.0% and the test has low positive predictive value of 46.8% in detecting bacteriuria in SCA patients. The significant pyuria observed in this study support its usefulness in the diagnosis of UTI among children with SCA especially in communities having limited facilities or personnel for carrying out urine culture.

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Section: Discussionmentioning

confidence: 99%

Significance of Pyuria in the Diagnosis of Urinary Tract Infection in Children with Sickle Cell Anaemia in Maiduguri, Nigeria

Mava¹,

Timothy²,

Zailani³

et al. 2012

Af J Clin Exp Micro

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“…Only small quantities of urine and of a cheap and stable reagent are required. There is no need for microscopy of negative specimens and the time saved can be more usefully applied to accurate cell counts for the remainder (Houston, 1969). Time is saved significantly when more than 500% of a batch are negative.…”

Section: Discussionmentioning

confidence: 99%

A blue catalase screening test for pyuria and haematuria

Thomas¹,

Baldwin²

1971

J Clin Pathol

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SYNOPSISThe blue catalase test is easy to perform and economical of materials. In a series of 529 adult female hospital patients it appeared to be a good screening test for pyuria and haematuria, detecting all but one of the specimens examined with more than 20 red and white cells combined per cubic millimetre of urine and 95-2 % of those with more than 10 cells. It indicates a raised leucocyte or red cell excretion rate but is not a test for bacteriuria.

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“…The presence of any leukocytes was chosen for the UTI definition, as the cutoff for pyuria is 10 or more leukocytes Â 10 6 /L (!1þ dipstick urinalysis). 27,28 The absence or presence of leukocytes in both diaper and reference specimens was defined as agreement, as from a clinical perspective, distinguishing the absence and presence of leukocytes is more relevant than determining the number of leukocytes in urine. For the UTI definition, a uniform growth cutoff of !10 4 CFU/mL was used for all uropathogens, as determinants of cutoff levels (eg, collection methods of reference specimens and the presence or urinary symptoms) were unknown.…”

Section: Primary Outcomementioning

confidence: 99%