Mean platelet volume as an indicator of disease severity in patients with acute pancreatitis

Beyazıt, Yavuz; Sayılır, Abdurrahim; Torun, Serkan; Suvak, Burak; Yeşil, Yusuf; Pürnak, Tuğrul; Öztaş, Erkin; Kurt, Mevlüt; Kekilli, Murat; İbi̇ş, Mehmet

doi:10.1016/j.clinre.2011.10.003

Cited by 98 publications

(90 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Although, MPV is an easily obtainable index from automated hematology analyzers, it has rather been overlooked until its associations with various diseases are continuously being reported recently. MPV is known to be decreased in diseases of acute pancreatitis, ulcerative colitis, rheumatoid arthritis and ankylosing spondylitis [9][10][11] as well as local inflammatory conditions including acute appendicitis (AA) due to migration and consumption of highly reactive large platelets into sites of inflammation [12]. AA is a common surgical emergency requiring timely intervention while its diagnosis can be elusive [13].…”

mentioning

confidence: 99%

Mean platelet volume in acute appendicitis: A gender difference

Yang

Cho²,

Hyung-jun

et al. 2013

Platelets

View full text Add to dashboard Cite

mentioning

confidence: 99%

Mean platelet volume in acute appendicitis: A gender difference

Yang

Cho²,

Hyung-jun

et al. 2013

Platelets

View full text Add to dashboard Cite

“…Mean platelet volume (MPV) is a parameter that is automatically measured when obtaining a complete blood count. In the literature, studies have investigated the relationships between MPV and many diseases such as stroke, myocardial infarction, pulmonary embolus, pancreatitis, diabetes mellitus, cancer, sepsis, hypertensive crisis, ulcerative colitis, ankylosing spondylitis and rheumatoid arthritis [2][3][4][5][6][7][8][9][10][11]. Recently, MPV has been reported to be helpful in the diagnosis of AA [12][13][14][15][16][17].…”

mentioning

confidence: 99%

Diagnostic Value of Mean Platelet Volume in Acute Appendicitis

Kılıç¹

2016

Ann Clin Anal Med

View full text Add to dashboard Cite

Anahtar KelimelerOrtalama Trombosit Hacmi; Cerrahi; Akut Apandisit; Acil Servis Abstract Aim: The diagnosis of acute appendicitis for patients referred to the emergency department with the complaint of abdominal pain remains challenging. In this study, we investigated the diagnostic value of mean platelet volume in acute appendicitis. Material and Method: This clinical research study was performed retrospectively and included patients referred to the emergency department between January 1 and December 31, 2013, with the complaint of abdominal pain and were then discharged without a specific diagnosis in comparison to patients with a proven diagnosis of acute appendicitis. Control patients were selected using a randomization method from among patients of the same age and gender as acute appendicitis patients. The acute appendicitis group was subdivided into complicated and noncomplicated cases according to the pathology results. The Mann-Whitney U test for continuous variables and the chi-square test for categorical data were used. Results: This clinical research study was performed with 316 acute appendicitis patients and an equal number of control patients; 188 of the patients were male. Among the acute appendicitis patients, 67 presented with complicated acute appendicitis and 249 with noncomplicated acute appendicitis. The median mean platelet volume of the acute appendicitis versus control patients was 8.03 fL (IQR: 1.86; min: 5.53, max: 14.40) and 8.10 fL (IQR: 1.38; min: 5.70, max: 13.90), respectively (p=0.193). The platelet counts in the complicated and noncomplicated groups were 235 K/µL (IQR: 70; min: 116, max: 649) and 261 K/µL (IQR: 87; min: 124, max: 537), respectively (p<0.001). Discussion: Mean platelet volume is not a useful guide in the diagnosis of acute appendicitis for patients referred to the emergency department with the complaint of abdominal pain.

show abstract

“…10 It has been suggested that the changes of MPV in many inflammatory diseases, such as inflammatory bowel diseases , 11,12 acute pancreatitis, 13,14 acute and chronic cholecystitis , 15 ankylosing spondylitis and rheumatoid arthritis, 16 and osteoarthritis with synovitis 17 are noteworthy.…”

Section: Discussionmentioning

confidence: 99%