Maternal Levels of Plasma Human Immunodeficiency Virus Type 1 RNA and the Risk of Perinatal Transmission

Garcia, Patricia; Kalish, Leslie A.; Pitt, Jane; Minkoff, Howard; Quinn, Thomas C.; Burchett, Sandra; Kornegay, Janet R.; Jackson, J. Brooks; Moye, John; Hanson, Celine; Zorrilla, Carmen; Lew, Judy

doi:10.1056/nejm199908053410602

Cited by 712 publications

(359 citation statements)

References 22 publications

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“…Additionally, the extended interval between laboratory assessment and delivery time is a limitation that may potentially compromise our findings and conclusions. Despite the significant difference between mean viral load in mother to child transmission and non-mother to child transmission, a threshold for predicting mother to child transmission was not established, similar to other studies (Mayaux et al 1997, Garcia et al 1999, ECS 2005, Read et al 2007.…”

Section: Discussionmentioning

confidence: 52%

Determinants and trends in perinatal human immunodeficiency virus type 1 (HIV-1) transmission in the metropolitan area of Belo Horizonte, Brazil: 1998 - 2005

Kakehasi

Pinto

Romanelli

et al. 2008

Mem. Inst. Oswaldo Cruz

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Section: Discussionmentioning

confidence: 52%

Determinants and trends in perinatal human immunodeficiency virus type 1 (HIV-1) transmission in the metropolitan area of Belo Horizonte, Brazil: 1998 - 2005

Kakehasi

Pinto

Romanelli

et al. 2008

Mem. Inst. Oswaldo Cruz

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“…Rates of transmission were reduced to approximately 2% with scheduled cesarean section and receipt of ZDV, which is similar to the rates of transmission seen among women with HIV-RNA levels less than 1000 copies/mL in the absence of systematic use of cesarean delivery (27,28). It is not known whether cesarean delivery offers any benefit when the mother is on effective antiretroviral therapy and/or when she has a low or undetectable plasma viral load.…”

Section: Prevention Of Perinatal Hiv Transmissionmentioning

confidence: 57%

“…HIV-RNA levels correlate with the risk of transmission in both antiretroviral treated and untreated women (27,28). The risk of perinatal transmission appears to be extremely low in women with undetectable plasma viral loads, which is the therapeutic goal with use of antiretroviral agents.…”

Section: Prevention Of Perinatal Hiv Transmissionmentioning

confidence: 99%

Human immunodeficiency virus and assisted reproduction: reconsidering evidence, reframing ethics

Lyerly

Anderson

2001

Fertility and Sterility

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“…Se ha mencionado ya en este y en otros estudios (32)(33)(34) que no es una enfermedad que tenga una connotación de culpabilidad, ya que adultos y menores tienen el mismo riesgo de contraerla.…”

Section: Discussionunclassified

Estigma, discriminación y adherencia al tratamiento en niños con VIH y SIDA: Una perspectiva bioética

et al. 2016

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Resumen: Investigación sobre el proceso de estigma y discriminación en niños con VIH y SIDA, y sus consecuencias en la adherencia al tratamiento desde una perspectiva bioética. Estudio deliberativo-hermenéutico con el uso de la narrativa en cuidadores primarios y en niños. Se aplicó cuestionarios para determinar la presencia de dichas variables y se realizó la interpretación de la información según la teoría de Paul Ricoeur, en tres momentos: respeto y estima de sí, relaciones interpersonales plenas y ética e instituciones justas. Se estudiaron once casos: seis niños y cinco niñas de los cuales solo tres fueron adherentes: dos y una respectivamente, comprobando la hipótesis de la influencia que el estigma y la discriminación ejercen sobre la adherencia al tratamiento; los casos detectados coincidieron con los de no adherencia al tratamiento. Se deliberó acerca de la problemática sugiriendo cursos de acción prudente en los tres niveles mencionados. Se mostró la importancia en el cuidado y la estima de los cuidadores primarios; ya que interviene en el desarrollo y percepción del síndrome en los niños. Palabras clave: VIH, niños, estigma, discriminación, adherencia al tratamiento Stigma, discrimination and adherence to treatment of children with HIV and AIDS. A bioethical perspectiveAbstract: This article discloses the results of an research into the process of stigma and discrimination in children with HIV and aids, and the impact they have on adherence from a bioethics perspective. It is a deliberative hermeneutical study using narrative in primary caregivers and children, questionnaires were applied to determine them the presence of these variables. The interpretation of the data was performed according to the theory of Paul Ricoeur, on three occasions: respect and esteem; fulfilling relationships; and ethical and fair institutions. Eleven cases were studied: 6 boys and 5 girls of which only three were adherents: 2 and 1 respectively. Hypothesis was tested for the influence that stigma and discrimination have on adherence to treatment; detected cases coincided with those of non-adherence to treatment. Discussion of the problem was performed suggesting courses prudent action in all three levels. The importance in caring and esteem showed primary caregivers; as it influences the development and perception of the syndrome in children.Key words: HIV, children, stigma, discrimination, treatment adherence Estigma, discriminação e aderência ao tratamento em crianças com HIV e AIDS. Uma perspectiva bioética Resumo: Investigação sobre o processo de estigma e discriminação em crianças com HIV e AIDS, e suas consequências na aderência ao tratamento a partir de uma perspectiva bioética. Estudo deliberativo-hermenêutico com a utilização da narrativa em cuidadores primários e em crianças. Foram aplicados questionários para determinar a presença das referidas variáveis e se realizou a interpretação da informação segundo a teoria de Paul Ricoeur, em três momentos: respeito e autoestima, relações interpessoais plenas e ética e i...

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Maternal Levels of Plasma Human Immunodeficiency Virus Type 1 RNA and the Risk of Perinatal Transmission

Abstract: In pregnant women with HIV-1 infection the level of plasma HIV-1 RNA predicts the risk but not the timing of transmission of HIV-1 to their infants.

Cited by 712 publications

References 22 publications

Determinants and trends in perinatal human immunodeficiency virus type 1 (HIV-1) transmission in the metropolitan area of Belo Horizonte, Brazil: 1998 - 2005

Determinants and trends in perinatal human immunodeficiency virus type 1 (HIV-1) transmission in the metropolitan area of Belo Horizonte, Brazil: 1998 - 2005

Human immunodeficiency virus and assisted reproduction: reconsidering evidence, reframing ethics

Estigma, discriminación y adherencia al tratamiento en niños con VIH y SIDA: Una perspectiva bioética

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