Maternal Asthma and Transient Tachypnea of the Newborn

Demissie, Kitaw; Marcella, Stephen; Breckenridge, Mary B.; Rhoads, George G.

doi:10.1542/peds.102.1.84

Cited by 82 publications

(59 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The prevalence of asthma among pregnant females is increasing [1][2][3]. Recent estimates in the USA suggest that 3.7-8.4% of pregnant females had asthma in 1997-2001, an increase from 3.2% from 1988-1994 [3].…”

Section: Asthma Prevalence In Pregnant Femalesmentioning

confidence: 99%

“…Two studies from New Jersey, based upon analysis of hospital records in 1989-1992, have examined neonatal [2] and maternal outcomes [14] in asthmatic females. Data from 2,289 asthmatic females were collected and compared to 9,156 control subjects.…”

Section: Historical Cohort Studiesmentioning

confidence: 99%

“…After adjustment for potential confounders, including age and education, asthmatic mothers also had an increased risk of pre-term labour, placenta previa, caesarean section, prolonged hospital stay and hypertensive disorders of pregnancy, including pre-eclampsia [14]. DEMISSIE et al [2] found an increase in transient tachypnoea of the newborn in infants of asthmatic mothers after accounting for confounding risk factors, such as caesarean delivery and premature birth. This association was stronger for male infants than female infants, possibly because male sex is a known risk factor for this condition [36], due to differences in foetal lung maturation between the sexes [37].…”

Section: Historical Cohort Studiesmentioning

confidence: 99%

“…Smoking, a contributor to low birth weight, has consistently been reported to be more common among asthmatics than nonasthmatics [1,2,6,15,27,29,35]. However, most studies have found that maternal smoking does not fully explain the association between asthma and adverse pregnancy outcomes [6].…”

Section: Summary: Effect Of Asthma On Pregnancymentioning

confidence: 99%

See 3 more Smart Citations

Asthma during pregnancy: mechanisms and treatment implications

Murphy

Gibson²,

Smith³

et al. 2005

European Respiratory Journal

155

View full text Add to dashboard Cite

Asthma is becoming increasingly prevalent worldwide. Numerous historical and prospective cohort studies have investigated the effects of maternal asthma on pregnancy outcome; however, the data has been conflicting and many studies have not used standard classifications for asthma severity. Overall, the literature suggests that asthmatic females are more at risk of low birth weight neonates, pre-term delivery and complications such as preeclampsia, especially in the absence of actively managed asthma treated with inhaled corticosteroids. Pregnancy with a female foetus may particularly increase the risk of these outcomes.In addition, pregnancy has an effect on the course of asthma. The risk of an exacerbation requiring medical intervention may be as high as 50% in females with severe asthma and this may further increase the risk of poor outcomes, particularly low birth weight and pre-term delivery.The mechanisms responsible for changes in asthma with pregnancy, or alterations in pregnancy outcomes due to asthma have not been thoroughly explored. Maternal inflammatory pathways may contribute to reduced foetal growth through alterations in placental function.Asthma treatment, by reducing maternal inflammation and preventing exacerbations, is safe for use in pregnant females and contributes to improved outcomes for both mother and foetus.

show abstract

Section: Asthma Prevalence In Pregnant Femalesmentioning

confidence: 99%

Section: Historical Cohort Studiesmentioning

confidence: 99%

Section: Historical Cohort Studiesmentioning

confidence: 99%

Section: Summary: Effect Of Asthma On Pregnancymentioning

confidence: 99%

See 2 more Smart Citations

Asthma during pregnancy: mechanisms and treatment implications

Murphy

Gibson²,

Smith³

et al. 2005

European Respiratory Journal

155

View full text Add to dashboard Cite

show abstract

“…It is also predictive of risk for chronic pulmonary diseases in childhood (2)(3)(4)(5). Survivors of respiratory distress syndrome with asthma and bronchopulmonary dysplasia consume 20 times more annualized dollars than unaffected children ($19,104 versus $955) and 5.9% of all dollars spent on children from 0 to 18 y of age (6).…”

mentioning

confidence: 99%