Mass Spectrometer Analysis of Some Oxygenated Compounds. The Sorption Problem

Mass Spectra of Trimethylsilyl Derivatives

“…Although mass spectrometric methods have been used to analyze mixtures of alcohols (1,6,7,9,16,17), determination of individual Cs to Cio primary alcohols in the presence of, hydrocarbons requires preliminary separation before chemical or spectroscopic methods can be applied. A method, utilizing the trimethylsilyl ether derivatives of alcohols, has been developed for rapid, direct analysis of individual alcohols in hydrocarbon solutions (IS).…”

Mass Spectrometric Analysis Broad Applicability to Chemical Research

“…THOUGH the primary use of the analytical mass spectrometer has been in routine quantitative analysis of light hydrocarbons, a number of investigators have reported on the unique qualitative and quantitative applications to the general field of chemistry, especially organic chemistry. The analytical advantages of the mass spectrometer for volatile oxygenated compounds (14, 18,21,22,35,36), thiophenes (19), aromatic hydrocarbons (19), lactones (13), acids (16), haloalkanes (1,26,35), amines (7), and metallo-organic compounds (8, 9) have been described. Significance of the spectra of such compounds as ketene dimer (23), pentaborane (10), diborane (28), dimethylphosphinoborine trimer (12), phenol, thiophenol, and aniline (27) has also been discussed.…”

The use of mass spectrometry in organic analysis

“…However, the presence of small amounts of water in an organic sample is not likely to cause difficulty. The seriousness of the sorption problem depends on the type of instrument and the type of analysis (27). Sensitivities tend to fluctuate and need to be redetermined from time to time for the pure standards.…”