Marjolin's ucler at a Nigerian hospital (1993–2003)

Onah, Ifeanyi Igwilo; Olaitan, Peter B; Ogbonnaya, IS; Onuigbo, Wilson Ib

doi:10.1016/j.bjps.2005.11.003

Cited by 16 publications

(12 citation statements)

References 5 publications

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“…Our survey confirms bleeding high frequency if you touch the lesion among the warning signs of cancer [24][25]. The ulceration (28.57%), are less frequent than burgeoning masses (71.43%) in our contrasting study with Chalya [24] whom reports 53.6% of burgeoning masses and Bauer [26] whom record ulcerations to all patients.…”

Section: Clinical Aspectssupporting

confidence: 75%

“…The ulceration (28.57%), are less frequent than burgeoning masses (71.43%) in our contrasting study with Chalya [24] whom reports 53.6% of burgeoning masses and Bauer [26] whom record ulcerations to all patients. The pain, the more often concomitant of local suppuration, are evenly identified among the call signs of malignant change [24][25]. The ulcerous forms are customarily predominant [13,15,27].…”

Section: Clinical Aspectsmentioning

confidence: 99%

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Marjolin's Ulcer: Seven (07) Cases Studied in Brazzaville

Malanda¹,

Kombo²,

Maye³

et al. 2019

IJCOCR

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Introduction Marjolin's Ulcer (MU) means all cutaneous malignancies developed on old unsteady scars. The general objective of this study was to report the MU cases in Congo with a literature review. It was a retrospective study conducted at University Teaching Hospital in Brazzaville from January 1998 to December 2017 (a 20-year period). The in-patients for cutaneous cancer histologically confirmed, arose on scarring skin lesions progressive were included. The epidemiological, clinical, histopathological and therapeutical variables were collected. Seven patients were identified. They represented 1.9% of skin cancers. The middle age was 44.4 years. The female predomination was noted with a sex ratio of 2.5. The burn scars was the etiological factor found to all our patients (100%). None of patients had an appropriate care of initial wound. The average time limit of the onset of MU was 34 years. The anatomopathologic examination revealed a squamous cell carcinoma to all our patients (100%). Carcinologic exeresis carried out to one (01) patient (14.28%). The amputation: three (03) patients (42.85%) and the disarticulation: two (02) patients (28.57%). The chemotherapy six (06) patients (85.71%). The decease arose five (05) patients (71.42%) and the entire remission reached to a woman patient (14.28%). This study confirmed the rareness and the severity MU; it also reveals the diagnosis lateness of a great death-rate. The care of quality of burns and chronic injuries, the awareness of patients together with the care givers training could help to improve the prognosis of this affection.

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Section: Clinical Aspectssupporting

confidence: 75%

Section: Clinical Aspectsmentioning

confidence: 99%

Marjolin's Ulcer: Seven (07) Cases Studied in Brazzaville

Malanda¹,

Kombo²,

Maye³

et al. 2019

IJCOCR

View full text Add to dashboard Cite

show abstract

“…In case a problem occurs in the wound healing process after surgery, active diagnosis and treatment may be urgently needed to improve the prognosis. With regard to the recurrence of carcinoma, Aydogdu et al [ 12 ] reported that, on average, 8 out of 12 patients experienced recurrence within 5.4 months (range, 3 to 10 months) after the surgery, and Onah et al [ 13 ] reported that there was recurrence in 11 out of 25 patients, including 5 cases of recurrence within 3 months, 2 cases of recurrence within 6 months, and 4 cases of recurrence within 1 year after the surgery. In our case, there was recurrence within 4.66±2.07 months (range, 2 to 8 months).…”

Section: Discussionmentioning

confidence: 99%

Impact of Disturbed Wound Healing after Surgery on the Prognosis of Marjolin's Ulcer

et al. 2013

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BackgroundMarjolin's ulcer is known to present a high proportion of recurrence and poor prognosis compared to other kinds of skin cancer. Based on our experience, Marjolin's ulcer patients who have received reconstructive surgery present a higher proportion of recurrence when there was disturbed wound healing after surgery. The impact of disturbed wound healing after surgery on the prognosis was examined in this study.MethodsA retrospective study was carried out on 26 patients who were diagnosed with Marjolin's ulcer and received surgery in this hospital from 1996 to 2011. Histologic grading, lymph node metastasis at diagnosis, and the wound healing process were evaluated and chi-squared analysis applied in order to determine the correlation with recurrence.ResultsThe proportion of recurrence increases in patients with a low histologic grade or lymph node metastasis at diagnosis. The proportion of recurrence is even higher when the problem occurs during the wound healing process after surgery.ConclusionsDisturbed wound healing after surgery could be used as a sign to quickly identify the recurrence of carcinoma. Therefore, in the event a problem occurs in the wound healing process after surgery, one should keep in mind that this could be a sign of the possibility of recurrence and proceed with careful observation and active diagnosis through additional physical examinations, general X-ray tests, computed tomographys, magnetic resonance imagings, and so on, to obtain an early diagnosis of recurrence.

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“…19 The incidence of Marjolin’s ulcer is higher in developing countries with limited medical resources, whereas it occurs in 1.6% to 23% of all patients with chronic osteomyelitis. 30-32 Marjolin’s ulcers mainly involve aggressive squamous cell carcinomas (SCC), with a latent period of 27 to 30 years from onset of osteomyelitis to malignant transformation. The long duration of chronic osteomyelitis is the single most important predictive factor.…”

Section: Complicationsmentioning

confidence: 99%

Chronic osteomyelitis: what the surgeon needs to know

2016

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Chronic osteomyelitis represents a progressive inflammatory process caused by pathogens, resulting in bone destruction and sequestrum formation.It may present with periods of quiescence of variable duration, whereas its occurrence, type, severity and prognosis is multifactorial.The ‘gold standard’ for the diagnosis of chronic osteomyelitis is the presence of positive bone cultures and histopathologic examination of the bone.Its management remains challenging to the treating physician, with a multidisciplinary approach involving radiologists, microbiologists with expertise in infectious diseases, orthopaedic surgeons and plastic surgeons.Treatment should be tailored to each patient according the severity and duration of symptoms, as well as to the clinical and radiological response to treatment.A combined antimicrobial and surgical treatment should be considered in all cases, including appropriate dead space management and subsequent reconstruction. Relapse can occur, even following an apparently successful treatment, which has a major impact on the quality of life of patients and is a substantial financial burden to any healthcare system.Cite this article EFORT Open Rev 2016;1:128–135. DOI: 10.1302/2058-5241.1.000017.

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Marjolin's ucler at a Nigerian hospital (1993–2003)

Cited by 16 publications

References 5 publications

Marjolin's Ulcer: Seven (07) Cases Studied in Brazzaville

Marjolin's Ulcer: Seven (07) Cases Studied in Brazzaville

Impact of Disturbed Wound Healing after Surgery on the Prognosis of Marjolin's Ulcer

Chronic osteomyelitis: what the surgeon needs to know

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Marjolin's ucler at a Nigerian hospital (1993–2003)

Cited by 16 publications

References 5 publications

Marjolin&apos;s Ulcer: Seven (07) Cases Studied in Brazzaville

Marjolin&apos;s Ulcer: Seven (07) Cases Studied in Brazzaville

Impact of Disturbed Wound Healing after Surgery on the Prognosis of Marjolin's Ulcer

Chronic osteomyelitis: what the surgeon needs to know

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Product

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Marjolin's Ulcer: Seven (07) Cases Studied in Brazzaville

Marjolin's Ulcer: Seven (07) Cases Studied in Brazzaville