Marine Algae: Their Products and Constituents

Hoppe, Heinz A.

doi:10.1515/9783110837506-003

Cited by 17 publications

(12 citation statements)

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“…For centuries, Greeks and Romans have used them as medicinal remedies and in cosmetics. In folk medicine, seaweeds have been utilised for a wide range of remedial purposes such as treatment of gallstone, vermifuges, stomach ailments, eczema, cancer and renal disorders (Hoppe and Lerving, 1982;Srivastava and Kulshreshtha, 1989). Presently, a variety of seaweeds have been used extensively in cosmetic applications.…”

Section: Introductionmentioning

confidence: 99%

Inhibitory effects of Sargassum polycystum on tyrosinase activity and melanin formation in B16F10 murine melanoma cells

Hwi

Cheah

2011

Journal of Ethnopharmacology

141

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Section: Introductionmentioning

confidence: 99%

Inhibitory effects of Sargassum polycystum on tyrosinase activity and melanin formation in B16F10 murine melanoma cells

Hwi

Cheah

2011

Journal of Ethnopharmacology

141

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“…28 Marine algae have been used for various purposes in food, industry and medicine. [29][30][31] Recently, edible seaweeds have been shown to exert many positive physiological effects, including antidiabetic complication, 32 antitumor, 33 hepatoprotective, 34 antiviral, 35 antiplasmin inhibitory, 36,37 algicidal, 38 tyrosinase inhibitory, 39 antiinflammatory, 40 nitrite-scavenging, 41 antiskin aging, 42,43 anticoagulative, 44 antiproliferative, 45 antioxidant 46,47 and antiallergic activities. 48 Ecklonia stolonifera Okamura is a perennial brown alga, belonging to the family Laminariaceae.…”

Section: Introductionmentioning

confidence: 99%

Acetyl- and butyrylcholinesterase inhibitory activities of sterols and phlorotannins from Ecklonia stolonifera

et al. 2008

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As part of this study on the isolation of cholinesterase inhibitors from natural marine products, the bioactivity of the ethanolic extracts from 27 Korean seaweeds were screened using acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory assays. Ecklonia stolonifera exhibited promising inhibitory properties against both AChE and BChE. Bioassay-guided fractionation of the active n-hexane and ethyl acetate (EtOAc) soluble fractions, obtained from the ethanolic extract of E. stolonifera, resulted in the isolation of the sterols; fucosterol (1) and 24-hydroperoxy 24-vinylcholesterol (2), from the n-hexane fraction and the phlorotannins; phloroglucinol (3), eckstolonol (4), eckol (5), phlorofucofuroeckol-A (6), dieckol (7), triphlorethol-A (8), 2-phloroeckol (9) and 7-phloroeckol (10), from the EtOAc fraction. Of these, compounds 2, 9 and 10 were isolated from E. stolonifera for the first time. Compounds 4-7, 9 and 10 exhibited inhibitory potential against AChE, with 50% inhibition concentration (IC50) values of 42.66 Ϯ 8.48, 20.56 Ϯ 5.61, 4.89 Ϯ 2.28, 17.11 Ϯ 3.24, 38.13 Ϯ 4.95 and 21.11 Ϯ 4.16 mM, respectively; whereas, compounds 1, 2, 4 and 6 were found to be active against BChE, with IC50 values of 421.72 Ϯ 1.43, 176.46 Ϯ 2.51, 230.27 Ϯ 3.52 and 136.71 Ϯ 3.33 mM, respectively. It has been suggested that the inhibition of these enzymes by the sterols and phlorotannins derived from marine brown algae could be a useful approach for the treatment of Alzheimer's disease.

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“…The health-promoting effects of algae were mentioned in Chinese medicine as early as 1500 BC (Hope, 1982). The health-promoting effects of algae were mentioned in Chinese medicine as early as 1500 BC (Hope, 1982).…”

Section: Schwimmer and Schwimmer (1955) In The Role Of Algae And Planmentioning

confidence: 99%

Medicinal Properties

Vonthron-Sénécheau

2016

Seaweed in Health and Disease Prevention

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Marine Algae: Their Products and Constituents

Cited by 17 publications

References 0 publications

Inhibitory effects of Sargassum polycystum on tyrosinase activity and melanin formation in B16F10 murine melanoma cells

Inhibitory effects of Sargassum polycystum on tyrosinase activity and melanin formation in B16F10 murine melanoma cells

Acetyl- and butyrylcholinesterase inhibitory activities of sterols and phlorotannins from Ecklonia stolonifera

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