Inhibitory effects of Sargassum polycystum on tyrosinase activity and melanin formation in B16F10 murine melanoma cells

Y, Chan Y; Hwi, Kim Kah; Cheah, Shiau‐Chuen

doi:10.1016/j.jep.2011.07.050

Cited by 141 publications

(100 citation statements)

References 20 publications

(20 reference statements)

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“…A number of plant polyphenols influenced the melanin biosynthesis and growth of various melanoma cells through their antityrosinase activity as well as antioxidant effects (4,5). Generally, B16-F10 murine melanoma cell line is an available model for studying the effects of extracts/compounds on melanin production.…”

Section: Discussionmentioning

confidence: 99%

“…Generally, B16-F10 murine melanoma cell line is an available model for studying the effects of extracts/compounds on melanin production. Although this cell line is similar in many melanogenic pathways with normal human 4 Int J Cancer Manag. 2017; 10(3):e4633.…”

Section: Discussionmentioning

confidence: 99%

“…ROS can cause extensive cellular damage and decrease enzymatic antioxidant defense. Based on these observations, melanogenesis is involved in several human skin disorders, including pigmentation disorders and melanoma (3)(4)(5). Therefore, suppressing melanogenesis through inhibition tyrosinase activity together with increasing antioxidant status can be an effective strategy to achieve both anti-melanogenic and antimelanoma properties.…”

Section: Introductionmentioning

confidence: 99%

“…Numerous studies have shown that some plant polyphenols influence the melanin biosynthesis and growth of various melanoma cells through their antityrosinase activity as well as antioxidant effect (4,5). The genus Phlomis (Lamiaceae) is rich with polyphenols (flavonoids and phenylethanoids/phenylpropanoids), iridoids and essential oils.…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of Anti-Melanogenic and Cytotoxic Activities of Phlomis caucasica on Human Melanoma SKMEL-3 Cells

et al. 2017

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Background: Under normal physiological condition, melanosomal melanin acts as a natural UV photoprotective filter. However, after long exposure to UV radiation, melanin has shown to involve in reactive oxygen species (ROS) generation and increases the risk of developing ageing, melasma and melanoma skin cancers. A number of plant polyphenols influenced the melanin biosynthesis and growth of various melanoma cells through their anti-tyrosinase activity as well as antioxidant effect.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Evaluation of Anti-Melanogenic and Cytotoxic Activities of Phlomis caucasica on Human Melanoma SKMEL-3 Cells

et al. 2017

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“…However, Chan et al (2011) reported that the tyrosinase assay using cells was a more credible method than the cell-free mushroom tyrosinase assay to screen skinwhitening compounds. This is mainly because the agents under evaluation target the tyrosinase derived from the melanin-producing cells as opposed to that of mushrooms.…”

Section: Inhibition Of Tyrosinase In B16f10 Cellsmentioning

confidence: 99%

Antimelanogenic effects of Inula britannica flower petal extract fermented by Lactobacillus plantarum KCCM 11613P

Park

Bae

Kim

et al. 2017

J. Zhejiang Univ. Sci. B

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Abstract:The inhibitory effects of Lactobacillus plantarum-fermented and non-fermented Inula britannica extracts on the tyrosinase activity were comparatively investigated to examine whether and how they improve the whitening activity, and the contents of total flavonoids and polyphenolics as bioactive compounds were determined. The skin whitening activity using in vitro or ex vivo tyrosinase and L-3,4-dihydroxyphenylalanine (L-DOPA) staining was examined. The total flavonoid content (TFC) was increased by 13.4% after 72 h-fermentation. The viabilities of the B16F10 cells treated with the fermented and non-fermented control extracts were 100.26% and 92.15% at 500 µg/ml, respectively. In addition, the inhibition of tyrosinase activity was increased by the fermented samples from 29.33% to 41.74% following fermentation for up to 72 h. The tyrosinase activity of the untreated control group was increased to 145.69% in B16F10 cells. The results showed that I. britannica fermented by L. plantarum dose-dependently inhibited tyrosinase activity, which was stimulated by α-melanocyte stimulating hormone. These results suggest that lactic fermented I. britannica extracts can be used as effective skin-whitening materials.

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Algae Cosmetics

Michalak

Dmytryk

Chojnacka

2020

Encyclopedia of Marine Biotechnology

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Inhibitory effects of Sargassum polycystum on tyrosinase activity and melanin formation in B16F10 murine melanoma cells

Cited by 141 publications

References 20 publications

Evaluation of Anti-Melanogenic and Cytotoxic Activities of Phlomis caucasica on Human Melanoma SKMEL-3 Cells

Evaluation of Anti-Melanogenic and Cytotoxic Activities of Phlomis caucasica on Human Melanoma SKMEL-3 Cells

Antimelanogenic effects of Inula britannica flower petal extract fermented by Lactobacillus plantarum KCCM 11613P

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