Modern Enterprise Innovation Management" is offered based on the introduction of enterprise management knowledge by focusing on the characteristics of modern food industry to improve economic benefits and highlight business decision-making. In this study, by integrating the concept of innovation and entrepreneurship education into the teaching reform of Modern Enterprise Innovation Management, this paper discusses in detail from the aspects of teaching content, teaching method, platform construction, assessment and evaluation, aiming at cultivating students' ability of innovation and entrepreneurship and solving practical problems, thus providing new ideas and directions for the future application-oriented curriculum reform. In terms of knowledge and skills, the teaching goal is to enable students to acquire the basic ideas and understand the basic methods of modern food enterprise management, enhance the awareness of food enterprise management, and cultivate the basic quality of enterprise management personnel with professional technology. At the same time, it integrates the new marketing model under the Internet of everything, family enterprise management, standardization and safety management, enterprise integrity management, entrepreneur self-management and patriotic feelings, and other new ecological enterprises' rapid evolution characteristics, so that students can adapt to the new needs of social and economic life. It is concluded that the realization of tangible construction, intangible construction and self-construction of food enterprises is the focus of teaching, and the use of specialized integration tools and thinking inspiration is the difficulty of teaching, and the teaching process integrates three methods: task-driven, behavior-oriented and role-playing. This study is of great significance to the development of higher education and food enterprises in the new era by exploring the methods and strategies of food enterprise management and innovation and entrepreneurship in colleges and universities.