Management of ART and COVID-19: Infertility in Times of Pandemic. What Now?

Souza, María do Carmo Borges de; Nakagawa, Hitomi; Taitson, Paulo Franco; Cordts, Emerson Barchi; Antunes, Roberto de Azevedo

doi:10.5935/1518-0557.20200031

Cited by 23 publications

(32 citation statements)

References 1 publication

(1 reference statement)

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“…28,52,59,61 Available data are from women infected during the third trimester, hence the COVID-19 effects on first trimester is unknown. 52,57,62 Conclusion COVID-19 has affected every part of the world, and it is likely to stay in the coming year. The potential risk of SARS-CoV-2 infection in reproductive systems, its effect on reproductive parameters and fertility cannot be ignored and hence warrants further quantitative research.…”

Section: Guidelines To Art Proceduresmentioning

confidence: 99%

“…While there is no clear evidence supporting vertical transmission, it cannot be ruled out due to COVID-positive placental and fetal membranes and neonates being tested positive after birth. 12,27,50,52,[57][58][59] Immunosuppression and hormonal fluctuation during pregnancy leave women more vulnerable to respiratory pathogens and severe pneumonia. 52 Nevertheless, there is no evidence stating increased susceptibility of COVID-19 in pregnancy.…”

Section: Guidelines To Art Proceduresmentioning

confidence: 99%

“…44 Pregnant women with COVID-19 also do not have symptoms more severe than non-pregnant women. 52,57,60 Although the exact pathogenesis of COVID-19 in pregnancy is unclear, pregnancy with COVID-19 is associated with more maternal and fetal complications. 52 These adverse pregnancy outcomes include preterm birth (most common), fetal distress, IUGR, increase caesarian sections, miscarriages, fetal, neonatal and maternal deaths.…”

Section: Guidelines To Art Proceduresmentioning

confidence: 99%

“…Individualization of each patient's ART treatment is the key to safe practice during this ongoing pandemic. 57…”

Section: Guidelines To Art Proceduresmentioning

confidence: 99%

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Potential COVID-19 Effects on Reproductive Systems and Fertility; ART Guidelines and Considerations: A Review

Lee

Mok

Chung

2020

Preprint

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The novel coronavirus SARS-CoV-2 was declared a pandemic on March 11, 2020. It utilizes angiotensin-converting enzyme 2 (ACE2) receptor in renin-angiotensin system (RAS) for viral entry. ACE2 is identified in female and male reproductive systems and reports of multi-organ involvement has led to uncertainty regarding its effects on reproductive systems and fertility. We review existing literature regarding function of ACE2 and RAS in reproductive systems to postulate the implications SARS-CoV-2 may have on fertility and assisted reproductive technology (ART) outcomes. ART guidelines from different fertility societies are provided for management of ART patients and for ART laboratory regulations.

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Section: Guidelines To Art Proceduresmentioning

confidence: 99%

Section: Guidelines To Art Proceduresmentioning

confidence: 99%

Section: Guidelines To Art Proceduresmentioning

confidence: 99%

“…Individualization of each patient's ART treatment is the key to safe practice during this ongoing pandemic. 57…”

Section: Guidelines To Art Proceduresmentioning

confidence: 99%

See 2 more Smart Citations

Potential COVID-19 Effects on Reproductive Systems and Fertility; ART Guidelines and Considerations: A Review

Lee

Mok

Chung

2020

Preprint

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“…In this case, patients should be allowed to continue their treatment in another ART referral center. However, proper and well-documented informed consents should be signed prior starting any ART treatment (Souza et al, 2020).…”

Section: Counseling and History Talkingmentioning

confidence: 99%

COVID-19: New adaptation for IVF laboratory protocols

Andrabi

Jaffar

Arora

2020

JBRA

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Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) widely known as COVID-19 was first reported in late December 2019, in China. Since then this novel coronavirus has spread throughout the world. Our return to normal life will not take long, for we are in a phase where the COVID-19 curve is stabilizing. ART services must return to operation, since infertility is also a disease and treatment has to start. Before resuming ART treatments, it is very important to consider local and national regulations. Change is mandatory, to set us back to successful ART treatment without compromising on quality, and to minimize the spread of COVID-19 among staff and patients; and for this we need to take measured and vigilant steps.

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