COVID-19: New adaptation for IVF laboratory protocols

Andrabi, Syed Waseem; Jaffar, Mir; Arora, Pallak

doi:10.5935/1518-0557.20200054

Cited by 16 publications

(30 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Exceptions were patients currently "in-cycle" or requiring urgent fertility preservation due to cancer treatment [3]. More recently, in Europe, with successful mitigation strategies against the pandemic, societies have allowed gradual resumption of ART procedures [4,5].…”

Section: Introductionmentioning

confidence: 99%

Psychological status of infertile patients who had in vitro fertilization treatment interrupted or postponed due to COVID-19 pandemic: a cross-sectional study

Barra

Rosa

Vitale

et al. 2020

Journal of Psychosomatic Obstetrics & Gynecology

View full text Add to dashboard Cite

Purpose: To explore the psychological status of infertile women and men who had in-vitro fertilization (IVF) treatment interrupted or postponed because of the COVID-19 emergency. Materials and methods: An electronic survey (NCT04400942) was e-mailed between April and June 2020 to couples whose IVF treatments have been interrupted or postponed due to the COVID-19 pandemic. The presence and severity of symptoms suggestive of anxiety and/or depression were assessed using the Generalized Anxiety Disorder-7 (GAD-7) and the Patient Health Questionnaire-9 (PHQ-9). Subjects with preexisting psychiatric disorders were excluded. Results: Overall, 524 out of 646 patients completed the survey. The prevalence of anxiety and/ or depression feelings was significantly higher in women, mainly if aged more than 35 years and with a previous IVF attempt. The occurrence of these psychological symptoms was significantly associated with the time spent on COVID-19 related news per day and partner with evidence of psychological disorder and, in females, with a diagnosis of poor ovarian reserve, diagnosis of endometriosis or uterine fibroids. Conclusions: The psychological impact of the COVID-19 pandemic on the infertile couples who should have undergone IVF treatment has been significant. IVF centers should systematically offer these couples adequate psychological counseling to improve mental health.

show abstract

Section: Introductionmentioning

confidence: 99%

Psychological status of infertile patients who had in vitro fertilization treatment interrupted or postponed due to COVID-19 pandemic: a cross-sectional study

Barra

Rosa

Vitale

et al. 2020

Journal of Psychosomatic Obstetrics & Gynecology

View full text Add to dashboard Cite

show abstract

“…However, there is evidence that more than 60% of COVID‐19 patients were identified to be asymptomatic and may spread virus (Qiu, 2020). Therefore, as Andrabi SW et al (Andrabi et al, 2020) reported, some stricter processes need to be implemented and our suggestions can be used as a supplement. Although the levels of messenger RNA might not be absolutely equal to protein, our finding supports the hypothesis that the chance of SARS‐CoV‐2 passing through germ cells to offspring is very low.…”

Section: Discussionmentioning

confidence: 99%

Suggestions on cleavage embryo and blastocyst vitrification/transfer based on expression profile of ACE2 and TMPRSS2 in current COVID‐19 pandemic

Cheng

Guo

Zhou

2021

Molecular Reproduction Devel

View full text Add to dashboard Cite

An outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is leading to an unprecedented worldwide health crisis. SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2. Our objectives are to analysis the expression profile of ACE2 and TMPRSS2 in human spermatogenic cells, follicle cells, and preimplantation embryos, thereby providing mechanistic insights into viral entry and viral impact on reproduction. We found that ACE2 is mainly expressed during gametogenesis in spermatogonia and oocytes of antral follicles, granulosa cells of antral follicles and pre-ovulatory follicles, while TMPRSS2 almost has no expression in spermatogenic cells, oocytes or granulosa cells. In preimplantation embryos, ACE2 is expressed in early embryos before eight-cell stage, and trophectoderm of late blastocysts, while TMPRSS2 initiates its robust expression in late blastocyst stage. ACE2 and TMPRSS2 only show significant co-expression in trophecto

show abstract

“…In COVID-19 positive patients, home collection and proper care can be an ideal way. Andrabi et al [17].…”

Section: Recommendation Based On Expert Opinionmentioning

confidence: 99%

IVF laboratory management in COVID-19 pandemic

Andrabi

Arora²,

Jaffar³

2021

jidhealth

Self Cite

View full text Add to dashboard Cite

Background: Since the first report of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), widely known as COVID-19, in late December 2019, it has spread worldwide. The eventual return of new normal has started to happen in most countries where the COVID-19 curve has flattened, and Assisted reproduction technology (ART) services are eventually resuming. Well-organized ART (embryology/andrology) laboratories safeguard the wellbeing of all staff, patients, and their gametes/embryos. Main body: A well-organized pandemic management plan must be implemented in anticipation of possible subsequent COVID-19 waves. Apart from local and national guidelines, some mandatory changes need to be taken into considerations that will allow us to overcome the fear of this deadly pandemic, work smoothly and stop any possible transmission without comprising the quality control for successful treatment. These mandatory changes include conserving different supplies, reducing manpower needs, and various protective measures for non-clinical and clinical staff, patients, and gametes/embryos. Conclusion: The current pandemic of COVID-19 suggests a well-organized action-oriented emergency plan to assure the wellbeing of all stakeholders.

show abstract

COVID-19: New adaptation for IVF laboratory protocols

Cited by 16 publications

References 12 publications

Psychological status of infertile patients who had in vitro fertilization treatment interrupted or postponed due to COVID-19 pandemic: a cross-sectional study

Psychological status of infertile patients who had in vitro fertilization treatment interrupted or postponed due to COVID-19 pandemic: a cross-sectional study

Suggestions on cleavage embryo and blastocyst vitrification/transfer based on expression profile of ACE2 and TMPRSS2 in current COVID‐19 pandemic

IVF laboratory management in COVID-19 pandemic

Contact Info

Product

Resources

About