Management of ankyloblepharon filiforme adnatum

Abstract

Sir, Management of ankyloblepharon filiforme adnatumAnkyloblepharon filiforme adnatum (AFA) is a rare congenital malformation affecting the eyelids. We report a case describing its management.

Eyes that cannot be seen: a rare case of ankyloblepharon filiforme adnatum (AFA) in a neonate

“…AFA is a rare condition which involves the unison of the upper and the lower eyelids by a single or multiple bands of tissue1 which arise posterior to the cilia 2. This can occur as an isolated condition or as a part of syndrome.…”

Eyelids, Eyelashes, and Eyebrows

“…It presents as single or multiple thin bands of fibrous tissue connecting the upper and lower eyelids (Hoyt and Taylor 2013). It can present either unilaterally or bilaterally (Ioannides and Georgakarakos 2011;Cizmeci et al 2013).…”

“…The isolated form of ankyloblepharon is the most common presentation (Ioannides and Georgakarakos 2011). The etiology of this form is currently unknown (Cizmeci et al 2013).…”

“…Congenital ankyloblepharon is also featured in popliteal pterygium syndrome (PPS, popliteal web syndrome, faciogenito-popliteal syndrome) (Ioannides and Georgakarakos 2011). This syndrome was previously believed to be of autosomal dominant inheritance caused by mutations in the IRF6 gene (Akkermans and Stern 1979;Qasim and Shaukat 2012).…”

“…Goldenhar's Syndrome (oculo-auriculo-vertebral dysplasia syndrome) is a craniofacial syndrome with no clear mode of inheritance Source: Ioannides and Georgakarakos (2011). Reproduced with permission from Macmillan.…”