2018
DOI: 10.1136/bcr-2018-224557
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Eyes that cannot be seen: a rare case of ankyloblepharon filiforme adnatum (AFA) in a neonate

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“…P63 is a gene on chromosome 3q27 that affects limb, craniofacial, and prenatal ectoderm development. [15] This anomaly's cause is unknown, although several hypotheses have been proposed. According to the currently accepted theory [13] , this condition is caused by temporary epithelial arrest and rapid mesenchymal proliferation, permitting abnormal lid union.…”
Section: Discussionmentioning
confidence: 99%
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“…P63 is a gene on chromosome 3q27 that affects limb, craniofacial, and prenatal ectoderm development. [15] This anomaly's cause is unknown, although several hypotheses have been proposed. According to the currently accepted theory [13] , this condition is caused by temporary epithelial arrest and rapid mesenchymal proliferation, permitting abnormal lid union.…”
Section: Discussionmentioning
confidence: 99%
“…The typical treatment for fibrous bands consists of their excision. Although some cases have resolved spontaneously before four months of age [15] , the advantages of early resection of the palpebral attachments are indisputable. Fine adhesion bands can be severed by forcibly separating the lids or using a muscle hook, pointed scissors, or a scalpel.…”
Section: Discussionmentioning
confidence: 99%