Multidisciplinary management of ankyloblepharon filiforme adnatum

Abstract

<jats:p>A female infant born at 41+6 weeks via emergency caesarean section due to failure to progress and maternal sepsis was found to have a small fibrous band connecting the upper and lower eyelids of the right eye. This was diagnosed as ankyloblepharon filiforme adnatum. The child was investigated for multisystemic malformations by the paediatric department, but none were found, and the partially fused right eyelid was dissected using microsurgical scissors to allow full opening of the eye. We summarise the management of a rare oculoplastic disorder.</jats:p>

Management of an Isolated Type I Ankyloblepharon Filiforme Adnatum (AFA) with Coloboma of the Upper Eyelid in a Newborn

“…[1], [4] Single or multiple bands of tissue may be evident in one or both eyes. [5] This is distinct from simple ankyloblepharon, in which the lid margins are fused directly. A central strand of vascular connective tissue is surrounded by squamous epithelium to form the tissue bands.…”

“…Type IV AFA is linked to labio-palatine fissures. A sixth type with the same characteristics as type I, but where there is also a family history of isolated congenital AFA transmitted by autosomal dominance, was proposed by Armes et al [5] .…”

“…Within the fifth month of pregnancy, the eyelids typically begin to form, and by the seventh month, they begin to separate into an upper and lower lid completely. [5] However, if there is a separation failure, it gives rise to AFA at the time of birth. [7], [8] Rosenman et al [8] divided AFA into four subgroups.…”

“…During the fifth month of pregnancy, the eyelids usually start to form, and by the seventh month, they have divided into an upper and lower lid. [5] Nonetheless, if separation fails to occur, AFA is present at birth. This case study illustrates the ease of treating the condition that a general ophthalmologist could do.…”