Malignant orofacial neoplasms in Lagos, Nigeria

Primary malignant neoplasms of orofacial origin: a retrospective review of 256 cases in a Nigerian tertiary hospital

“…Oral malignant neoplasms are the sixth most common malignancy in the world, and when malignancy of the pharynx is included they account for the third most common malignancy in the developing world 13,34 . Global epidemiology shows that head and neck cancers constitute between 5% and 50% of all cancers, and the orofacial region has been reported to be a common site 4,20 . Many studies have shown that the wide variation in incidence of oral malignant neoplasia across the world can be partly explained by the difference in prevalence of the Primary malignant neoplasms of orofacial origin 405 Total 4 7 3 38 58 6 26 8 2 12 13 177…”

“…There have been few reports published on malignant lesions of the orofacial region in an African environment 4,13,17 . The present study reviews 256 consecutive cases of orofacial malignant lesions seen over a 12-year period (1992-2003) at the Lagos University Teaching Hospital, Nigeria, with a view to highlighting age, gender, site distribution and histologic variants.…”

Oral Cancer- The Nigerian Perspective

“…However, some other contrasting studies have stated mandibular gingiva as the most common site of occurrence followed by the maxillary gingiva and the tongue [44]. The maxillary antrum is observed as the most common site in other studiesin Lagos [19,52]. Figures 1 and 2 shows a clinical photograph of Squamous cell carcinoma (SCC) of the tongue and Mucoepidermoid Carcinoma of the palate respectively while Figure 3 is that of a young male with Burkitt's lymphoma affecting the jaws.…”

“…Orofacial carcinoma is reported as the most common malignancy known to affect the oral and maxillofacial region in our environment. Arotiba et al [52] and Ajayi et al [19] in Lagos, South-west, Nigeria have reported a prevalence of 68.2% and 69% respectively for carcinomas among the oral cancers. Arotiba et al [52] 2006 found the carcinomas as consisting mostly of SCC (42.9%) and salivary gland carcinomas (25.4%).…”

“…Arotiba et al [52] and Ajayi et al [19] in Lagos, South-west, Nigeria have reported a prevalence of 68.2% and 69% respectively for carcinomas among the oral cancers. Arotiba et al [52] 2006 found the carcinomas as consisting mostly of SCC (42.9%) and salivary gland carcinomas (25.4%). They observed socio-economic group which makes them present late in our health care facilities for treatment hence a poor prognosis.…”