Primary malignant tumors of orofacial region at Benghazi, Libya: A 17 years review

Subhashraj, Krishnaraj; Orafi, Maraai; Nair, Kavita V.; El-Gehani, R.; Elarbi, M.

doi:10.1016/j.canep.2009.10.009

Cited by 32 publications

(65 citation statements)

References 27 publications

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“…In our study, the prevalence of OSCC among the oral biopsied lesions was 36.1%. A much lower prevalence was found in Spain (1.4%),11 Brazil (2.5%),22 Libya (8%),23 Nigeria (10.8%)24 and the (UAE) 14.9% 17. The higher frequency of OSCC in our series can be correlated to the local habit of shammah usage in the Jazan region.…”

Section: Discussioncontrasting

confidence: 51%

Retrospective analysis of biopsied oral and maxillofacial lesions in South-Western Saudi Arabia

Saleh

Idris

Vani

et al. 2017

SMJ

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Objectives:To report the prevalence and types of biopsied oral and maxillofacial lesions (OMLs) in South-Western (Jazan Province) region, Kingdom of Saudi Arabia (KSA).Methods:This retrospective study was based on the retrieval of clinicopathological data for a period of 6 years between January 2009 and December 2014. These data were obtained between October 2014 and June 2015 from the histopathology records of King Fahad Central Hospital, Jazan, KSA, which is the only referral center for biopsy services.Results:Out of the 32149 biopsies received, 714 (2.2%) were OMLs. The age ranged from 0 (neonatal) to 100 years, with a mean age of 46.8±23.4 and a male-to-female ratio of 1:1.3. The tongue was the most common site for OMLs and for malignant neoplasms, in particular. The most common category was malignant neoplasm (38.7%), followed by inflammatory lesions (16.5%). Oral malignancies accounted for 15.8% of all malignancies. Oral squamous cell carcinoma (OSCC) (36.1%) was the most frequent type, followed by pyogenic granuloma and mucocele (7% each). Shammah-associated OSCC and epithelial dysplasia were twice as common in females.Conclusion:The number of non-malignant OMLs was much lower than expected in comparison to oral malignancies. This difference can likely be explained by the fact that the biopsies were taken only when malignancy was suspected. The higher rate of OSCC reported from this region is attributed to shammah usage. This study emphasizes the importance of biopsy services for all OMLs and the prevention of shammah use.

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Section: Discussioncontrasting

confidence: 51%

Retrospective analysis of biopsied oral and maxillofacial lesions in South-Western Saudi Arabia

Saleh

Idris

Vani

et al. 2017

SMJ

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“…The most prevalent diagnosis of all oral biopsies was OSCC, which accounted for 77% of all oral malignancies. A much lower proportion was reported by a study conducted in Libya (41%) (12). Conversely, OSCC constituted a higher proportion of oral malignancies in Jordan (84%) (15), Malaysia (91.3%) (16), and Pakistan (92.2%) (13).…”

Section: Discussionmentioning

confidence: 58%

“…This differed slightly from the findings in Brazil and Sri Lanka, where the M:F ratio was 3:1 (11, 19). Lower M:F ratios were seen in Iraq (2:1) (20), Jordan (1.77:1) (15), Libya (1.61:1) (12), Pakistan and Nigeria (1.4:1) (13, 21), Iran and Thailand (1.3:1) (22, 23), Yemen (1.24:1) (24), and Malaysia (0.92:1) (16). Gender is not a risk factor per se for oral cancer.…”

Section: Discussionmentioning

confidence: 99%

“…In this report, we compare the pattern of oral cancer with that in countries with some similarities with the UAE population. In this regard, the disease appears in 1.8%, 1.4%, 0.4%, 2.5%, and 8% of the oral biopsies reviewed in a Turkish, Spanish, Cambodian, Brazilian, and Libyan population, respectively (8–12). These were much lower than the prevalence of malignant tumors found in our series, which was 14.9% of all oral biopsies.…”

Section: Discussionmentioning

confidence: 99%

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Oral cancer in the UAE: a multicenter, retrospective study

Anis

Gaballah

2013

Libyan Journal of Medicine

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AimTo determine the prevalence of various malignant oral lesions in the UAE and correlate cases of squamous cell carcinomas with age, gender, site, grade, clinical presentations at the time of diagnosis, and the prevalence of neck metastasis.Materials and methodsA multicenter, retrospective study was conducted at four major hospitals in the UAE. The study was based on histopathology reports of biopsies of oral tissues.ResultsOf the 992 oral biopsy reports retrieved, 147 cases of malignant tumors were found which accounted for 14.9% of the total biopsies. Fifteen different types of malignant lesions were diagnosed, of which oral squamous cell carcinoma (OSCC) was the most prevalent and made up 11.4% of the overall oral biopsies retrieved. The commonest presentation of cancer was ulceration (31.17%), followed by lumps and white lesions. The most common site where the lesions were diagnosed was the tongue (51.9%), followed by the cheeks and lips. OSCC accounted for 77% of all malignancies reported. Neck dissections were conducted in only 20.8% of all OSCC cases diagnosed at Mafraq and Tawam hospitals, of which 43.75% showed evidence of neck metastasis.ConclusionOral cancer is not an uncommon disease in the UAE. This may mandate more awareness campaigning, including screening procedures for early detection of cancerous lesions and other potentially malignant oral diseases. Elective neck dissections to detect lymph node metastasis should be more routinely performed, in particular for tongue carcinomas because of the early neck involvement potential.

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“…20 The site variations could be attributed to the intensity of exposure to different risk factors prevalent worldwide. Moreover Subashrajet al 21 reported that the high risk relating these sites is due to saliva mixed with carcinogens constantly bathe these sites and the thinner, non-keratinized mucosa lining these sites offer decreased protection against carcinogens.…”

Section: Discussionmentioning

confidence: 99%

A Study of 89 Cases of Oral Squamous Cell Carcinoma Presenting at Teaching Hospitals of Lahore, Pakistan

Sahaf¹,

Naseem²,

Rehman³

et al. 2017

J Pak Dent Assoc

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ABSTRACT:OBJECTIVE: Oral squamous cell carcinoma (OSCC) is one of the most prevalent malignant neoplasm in south Asia and a major public health problem in Pakistan due to its high morbidity and poor survival rates. The objective of the study was to describe the clinical pattern of oral squamous cell carcinoma in tertiary care hospitals of Lahore. METHODOLOGY:A cross sectional study was done at tertiary care hospitals of Lahore where demographic and clinical data of eighty nine histologically diagnosed cases of OSCC was studied. RESULTS:Mean age of the patients was 53.13 ±14.82 years and male to female ratio was 1.4:1 with 58.4%males and 41.6% females. Tongue was the most frequently affected site 37.1%followed by buccal mucosa 30.3%. The most common presenting complaint was non healing ulcer 50.6%.Mean duration of lesions at presentation was 5 ± 3.68 months. 66.3% cases reported with history of smoking, chewing tobacco/snuff and betel quid. Smoking was the most prevalent etiological agent accounting for 22.5% cases and was found to be significantly higher in the male population (p<0.001). CONCLUSIONS:Most cases of oral squamous cell carcinoma (OSCC) in major hospitals of Lahore, Pakistan are reported in 5th to 6 th decade of life, with male preponderance. Ulceration is the most common clinical manifestation in OSCC patients with about two-third cases reporting within 6 months of onset of lesions. Tongue is the most commonly affected site and smoking tobacco and betel quid chewing are the main risk factors implicated in OSCC.

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Primary malignant tumors of orofacial region at Benghazi, Libya: A 17 years review

Cited by 32 publications

References 27 publications

Retrospective analysis of biopsied oral and maxillofacial lesions in South-Western Saudi Arabia

Retrospective analysis of biopsied oral and maxillofacial lesions in South-Western Saudi Arabia

Oral cancer in the UAE: a multicenter, retrospective study

A Study of 89 Cases of Oral Squamous Cell Carcinoma Presenting at Teaching Hospitals of Lahore, Pakistan

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