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citations
Cited by 39 publications
(61 citation statements)
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References 34 publications
(46 reference statements)
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“…When RDTs were used as the reference standard, nPCR exhibited sensitivity and positive values of 100% and 39.38% respectively. This ability for PCR to more accurately detect low-grade parasitemia with a higher degree of sensitivity than microscopy and RDTs supports the reports by other researchers [22], [27][28][29][30]. The high false negative obtained using RDTs has been reported and suggested that all RDT negative results be confirmed by microscopic analysis [31].…”
Section: Discussionsupporting
confidence: 86%
“…When RDTs were used as the reference standard, nPCR exhibited sensitivity and positive values of 100% and 39.38% respectively. This ability for PCR to more accurately detect low-grade parasitemia with a higher degree of sensitivity than microscopy and RDTs supports the reports by other researchers [22], [27][28][29][30]. The high false negative obtained using RDTs has been reported and suggested that all RDT negative results be confirmed by microscopic analysis [31].…”
Section: Discussionsupporting
confidence: 86%
“…One sample was positive for P. malariae by PCR [19]. Recently, samples of 39 donors from the same area were assayed employing a modified real-time PCR protocol [20] using genus-specific primers [17]. ELISA- Pv was reagent in 38% of samples and SD Bioline Pf / Pv was positive in 38% ( Pv band) and 0% ( Pf band).…”
Section: Introductionmentioning
confidence: 99%
“…PCR techniques are highly sensitive for the detection of parasite nucleic acids [7][8][9], are particularly valuable for species confirmation and should be used in all instances when species cannot be determined by microscopy or to evaluate for mixed infections [5] but unfortunately are not always available everywhere. Immunochromatographic tests most often using a dipstick or a cassette format contain monoclonal antibodies against parasite specific antigens and provide results in 5-20 minutes [10,11].…”
Section: Discussionmentioning
confidence: 99%