Magnetic Nanoparticles: Functionalization and Manufacturing of Pluripotent Stem Cells

Horie, Masanobu; Tripathi, Anuj; Ito, Akira; Kawabe, Yoshinori; Kamihira, Masamichi

doi:10.1007/978-981-10-3328-5_9

Cited by 4 publications

(3 citation statements)

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“…Besides that, some of their properties are saturation magnetization, coercivity, blocking temperature, and relaxation time. These magnetic properties are influenced by their syntheses and features such as particles size, shape, and composition; and also the presence of a core-shell design [130,131].…”

Section: Magnetic Nanoparticlesmentioning

confidence: 99%

“…The particles presented an average diameter of 30 nm and could be used in a Rod-like HA particle. These nanoparticles' heating characteristic is their advantage, which could be used for cancer treatment under a magnetic field [130]. In addition to this combination, nanocrystalline HA particles blended with magnetite (Fe 3 O 4 ) forming Fe 3 O 4 −HA nanoparticles have also been studied.…”

Section: Magnetic Nanoparticles As Part Of Composites For Drug Deliverymentioning

confidence: 99%

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Drug-delivery nanoparticles for bone-tissue and dental applications

Higino¹,

França²

2022

Biomed. Phys. Eng. Express

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The use of nanoparticles as biomaterials with applications in the biomedical field is growing every day. These nanomaterials can be used as contrast imaging agents, combination therapy agents, and targeted delivery systems in medicine and dentistry. Usually, nanoparticles are found as synthetic or natural organic materials, such as hydroxyapatite, polymers, and lipids. Besides that, they are could also be inorganic, for instance, metallic or metal-oxide-based particles. These inorganic nanoparticles could additionally present magnetic properties, such as superparamagnetic iron oxide nanoparticles. The use of nanoparticles as drug delivery agents has many advantages, for they help diminish toxicity effects in the body since the drug dose reduces significantly, increases drugs biocompatibility, and helps target drugs to specific organs. As targeted-delivery agents, one of the applications uses nanoparticles as drug delivery particles for bone-tissue to treat cancer, osteoporosis, bone diseases, and dental treatments such as periodontitis. Their application as drug delivery agents requires a good comprehension of the nanoparticle properties and composition, alongside their synthesis and drug attachment characteristics. Properties such as size, shape, core-shell designs, and magnetic characteristics can influence their behavior inside the human body and modify magnetic properties in the case of magnetic nanoparticles. Based on that, many different studies have modified the synthesis methods for these nanoparticles and developed composite systems for therapeutics delivery, adapting, and improving magnetic properties, shell-core designs, and particle size and nanosystems characteristics. This review presents the most recent studies that have been presented with different nanoparticle types and structures for bone and dental drug delivery.

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Section: Magnetic Nanoparticlesmentioning

confidence: 99%

Section: Magnetic Nanoparticles As Part Of Composites For Drug Deliverymentioning

confidence: 99%

Drug-delivery nanoparticles for bone-tissue and dental applications

Higino¹,

França²

2022

Biomed. Phys. Eng. Express

View full text Add to dashboard Cite

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“…磁性纳米颗粒被大量应用于生物医学领域, 在不同的应用方式下, 磁性材料的形态以及存在环境也是不同的. 例如将磁性纳米颗粒组装到细胞上实现通过外磁场对细胞的调控 [48] , 或者研究细胞不同包覆的磁性纳米颗粒吞噬能力的差别 [49] , 以及磁性纳米颗粒在细胞中的降解过程 [50] , 这些种种研究都涉及对于材料磁性的评估. 由于纳米磁性颗粒在被吞噬到细胞内部之后, 其聚集状态会发生改变, 有研究还发现磁性纳米材料被不同器官细胞吞噬后其降解过程都会有所差异 [51] , 因此我们需要对这些生理环境中的磁性材料进…”

Section: 类生理环境中磁性纳米颗粒磁性测量算法验证unclassified