Magnetic impedance biosensor: A review

Wang, Tao; Zhou, Yong; Lei, Chong; Luo, Jun; Xie, Shaorong; Pu, Huayan

doi:10.1016/j.bios.2016.10.031

Cited by 108 publications

(67 citation statements)

References 109 publications

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“…Although magnetic label detection in the regime of immobilized markers was shown to be most accurate protocol, the possibility of free label detection was also widely discussed [4,25]. Successful detection of the magnetic labels is possible only when a number of requests are satisfied.…”

Section: Resultsmentioning

confidence: 99%

“…GMI has been proposed as a powerful technique for biosensing based on the magnetic label detection or label-free sensing process. In the first case the change of the impedance of sensitive element under the application of an external magnetic field is analyzed in the presence of magnetic nanoparticles (MNPs) in a test solution and the origin of the sensitivity is clearly connected with the stray fields crated by the MNPs [3,4]. In the second case if rapidly quenched ribbon sensitive element is employed the advantage of natural nonuniform magnetic anisotropy was taken [5].…”

Section: Introductionmentioning

confidence: 99%

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Magnetoimpedance Effect in CoFeMoSiB As-Quenched and Surface Modified Amorphous Ribbons in the Presence of Igon Oxide Nanoparticles of Water-Based Ferrofluid

et al. 2017

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Giant magnetoimpedance (GMI) has been proposed as a powerful technique for biosensing. In GMI biosensors based on the magnetic label detection the change of the impedance of sensitive element under the application of an external magnetic field was analyzed in the presence of magnetic nanoparticles in a test solution. Amorphous ribbon-based GMI biodetectors have an advantage of low operation frequency and low cost. In this work, magnetic and GMI properties of amorphous Co 68.6 Fe 3.9 Mo 3.0 Si 12.0 B 12.5 ribbons were studied in as-quenched and surface modified states both without and in the presence of maghemite ferrofluid. After the surface modification the coercivity was slightly increased and saturation magnetization decreased in good agreement with increase of the surface roughness, a decrease of magnetic elements concentrations in the surface layer, and formation of a surface protective oxide layer. The GMI difference for as-quenched ribbons in absence and in the presence of ferrofluid was measurable for the frequency range of 2 to 10 MHz and the current intensities of 1 to 20 mA. Although the proposed surface modification by the ultrasound treatment did not improve the sensitivity limit for ferrofluid detection, it did not decrease it either.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Magnetoimpedance Effect in CoFeMoSiB As-Quenched and Surface Modified Amorphous Ribbons in the Presence of Igon Oxide Nanoparticles of Water-Based Ferrofluid

et al. 2017

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“…Combination of methods involving biolabels and nanoparticles provided new technological advances in drug delivery, more importantly for targeted therapy in biomedicine (Chen et al., ) which is central to counter several infectious diseases as well (Sin, Mach, Wong, & Liao, ). Label‐free detection methodology in biosensors with micro‐ and nano‐fabrication made enough progress in the field with principles of electrochemistry, magnetism and optics (Sang, Wang et al., ; Wang, Xu et al., ; Wang, Zhou et al., ). Although electrochemical sensors showed dominance in biosensing technological advancements, novel methods with fluorescence label and nanoparticles created a sensational new wave of optical and SPR‐based biosensors with high specificity and selectivity in tag track detection (Cheng et al., ; Tamura & Hamachi, ; Turner, ).…”

Section: Modern Era Biosensors: Combination Of Biolabels and Nanomatementioning

confidence: 99%

“…Conversely, biolabels are novel tools of biosensors wherein targeted “electronic skin” detects chemical ingredients in physiological or security analysis in biomedicine or forensic science (Windmiller, Bandodkar, Parkhomovsky, & Wang, ; Windmiller, Bandodkar, Valdes‐Ramirez et al., ). Thus, hi‐tech network integrated approach of biosensors, nanoparticle devices and biolabels provides new inventions in the fields of biosensing and bioimaging by using the principles of electrochemistry, optics, SPR and magnetics with micro‐ or nano‐fabrication which in course paved way for developing modern‐day sensors (Sang, Chou, Pan, & Sheu, ; Sang, Feng et al., ; Sang, Wang et al., , 2016; Torun et al., ; Wang, Xu et al., ; Wang, Zhou et al., ). In view of current as well as future biosensing applications using biolabels and nanomaterials, present review concisely highlights the technology with a focus on the discovery, principle, chemistry, types, design and technical supremacy in terms of specificity, sensitivity, portability in addition to affordability of biosensors at nanoscale for versatile applications.…”

Section: Introductionmentioning

confidence: 99%

Current technological trends in biosensors, nanoparticle devices and biolabels: Hi‐tech network sensing applications

Vigneshvar

Senthilkumaran

2018

Med Devices & Sens

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Biosensors are micro‐analytical devices usually coupled to a bio‐integrated transducer that emits signal to measure specific molecules as an analyte, either qualitatively or quantitatively for various downstream applications. Improved detection methods at quantum level in nanoscale became a reality due to the invention of integrated circuits involving nanoparticle devices and biolabels. Next level of discoveries leads to the identification of novel particulates to improve the specificity and sensitivity for single analyte detection. Although different kinds of biosensors show promise for multifaceted applications in science and technology, certain limitations do exist in terms of portability, selectivity and sensitivity as well as in multi‐analyte detection. Recent methodical advancements involving nanomaterials or nanoparticles/metals in combination with biomarkers or biolabels as sensors provide new insights to solve these limitations to prepare flawless detecting devices. These technical advances are evident in modern‐day sensors including hand‐held, smartphone‐based, wearable and flexible sensors developed for multifaceted applications. This concise review article describes the new technological trends in the development of biosensors integrated to nanoparticle devices and/or biolabels involving hi‐tech network system for better efficiency. Future perspectives on new technological developments for effective combination of several nanomaterials and biolabels with strategic engineering methodology were highlighted.

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“…Those were exhaustively reviewed recently [72]. Among the different materials used, besides wires and ribbons, thin film structures have been demonstrated to be able to detect microparticles in a flowing liquid [73] and nanoparticles embedded in gels (ferrogel) [74].…”

Section: Brief Survey Of Applicationsmentioning

confidence: 99%

Thin-Film Magneto-Impedance Sensors

Garcı́a-Arribas¹,

Férnández²,

Cos³

2017

Magnetic Sensors - Development Trends and Applications

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We review the state-of-the-art of thin films displaying the magneto-impedance (MI) effect, with focus on the aspects that are relevant to the successful design and operation of thin film-based magnetic sensors. After a brief introduction of the MI effect, the materials and geometries that maximize the performance, together with the measurement procedure for their characterization, are exposed. A nonexhaustive survey of applications is included, mostly with the aim of displaying the capabilities of thin film structures in the field of magnetic sensing, and the variety of topics covered by them. A special emphasis is made on some concepts that are not commonly treated in the literature, such as the influence of the measuring circuit on the magneto-impedance ratio, the geometry optimization by means of numerical simulation by finite element methods, or noise measurements on thin films. Additionally, a brief description of the patterning procedure by photolithography is included, since the major advantage of thin film sensors over other types of magneto-impedance materials as ribbons or wires is the possibility of patterning the sensible element in micrometric shapes, and most of all, their easy integration with the interface microelectronic circuitry.

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Magnetic impedance biosensor: A review

Cited by 108 publications

References 109 publications

Magnetoimpedance Effect in CoFeMoSiB As-Quenched and Surface Modified Amorphous Ribbons in the Presence of Igon Oxide Nanoparticles of Water-Based Ferrofluid

Magnetoimpedance Effect in CoFeMoSiB As-Quenched and Surface Modified Amorphous Ribbons in the Presence of Igon Oxide Nanoparticles of Water-Based Ferrofluid

Current technological trends in biosensors, nanoparticle devices and biolabels: Hi‐tech network sensing applications

Thin-Film Magneto-Impedance Sensors

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