M-mode, 2-D and Doppler echocardiographic study in 65 patients with Behçet's syndrome

Özkan, Mehmet; Emel, O.; Özdemir, Mehmet; Yurdakul, Sebahattin; Koçak, Hikmet; Özdoğan, Huri; Hamuryudan, Vedat; Dırıcan, Ahmet; Yazıcı, Hasan

doi:10.1093/oxfordjournals.eurheartj.a060228

Cited by 65 publications

(34 citation statements)

References 5 publications

(6 reference statements)

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“…24,25 In our study, MVP was not detected in the patient or control group. These discrepancies may be related to strictly applied echocardiographic diagnostic criteria for MVP in our study.…”

Section: Discussioncontrasting

confidence: 57%

Cardiovascular Involvement in Behçet's Disease

et al. 2015

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Section: Discussioncontrasting

confidence: 57%

Cardiovascular Involvement in Behçet's Disease

et al. 2015

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“…Transthoracic echocardiography (TTE) has been used for detecting cardiac abnormalities in previously published studies. 2,3) In this study, we performed TTE and then transesophageal echocardiography (TEE) to evaluate cardiac involvement in Behçet's disease patients and also to determine if there is a relationship between these echocardiographic findings and repolarisation abnormalities.…”

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confidence: 99%

Cardiovascular Involvement in Behcet's Disease.

et al. 2002

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SUMMARYThe incidence and nature of cardiac involvement in Behçet's disease are not yet clearly documented. We first used transesophageal echocardiography in combination with resting and signal averaged electrocardiography to define cardiac involvement in Behçet's patients. Transthoracic and multiplane transesophageal echocardiography, and resting and signal averaged electrocardiography were performed in 35 Behçet's disease patients (9 women and 26 men, mean age: 38±12 years) and 30 normal subjects. Higher incidences of interatrial septum aneurysm (31% to 6%), mitral valve prolapse (25% to 3%), mitral regurgitation (40% to 6%) and aneurysmal dilatations of sinus valsalva and ascendan aorta were observed in the Behçet's disease patients than in the normal subjects. Mean QT dispersion and mean corrected QT dispersion values were significantly greater in the patients with Behçet's disease. Patients with interatrial septum aneurysm (and/or PFO), valvular dysfunction or proximal aorta dilatation had greater QT dispersion values than thase without these pathologies in the Behçet's group (63±11 vs 44±19 ms, 58±23 vs 41±24 and 60±27 vs 42±23 ms respectively, P<0.05). Positive signal averaged electrocardiography parameters were detected in 18 (51%) Behçet's disease patients compared with one (3%) in controls (P<0.001). Dilatation of the proximal aorta, interatrial septal aneurysm, mitral valve prolapse, and mitral regurgitation are the common findings of cardiac involvement in Behçet's disease. Increased dispersion of ventricular repolarisation and positive late potentials are also detected. QT dispersion is significantly higher in patients with these cardiac abnormalities. These findings suggest that cardiac involvement in this disorder is a diffuse process which involves both cardiac structure and vascular elements. (Jpn Heart J 2002; 43: 389-398) Key words: Echocardiography, Electrocardiography, Behçet's disease BEHÇET'S disease is known as a chronic relapsing, inflammatory process manifesting recurrent oral and genital aphthous ulcerations. Eye inflammation, skin lesions of erythema nodosum and acneiform eruptions, joint, central nervous system, large vessel and gastrointestinal system tract involvement are also seen in From the

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“…In a series of 137 BD patients only one case of intracardiac thrombus was described (5). Ozkan et al (6) demonstrated that there is no difference in the prevalence of echocardiographic abnormalities between patients with BD and control subjects. Since the first description by Buge in 1977 (7) up to date, only about 50 cases have been reported (1,2,(8)(9)(10)(11)(12)(13)(14)(15)(16)(17).…”

Section: Discussionmentioning

confidence: 99%

Intracardiac Thrombus in a Young Man: Don't Forget Behçet's Disease!

et al. 2012

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Intracardiac thrombosis is an exceptional complication of Behçet's disease. The management of this involvement is difficult due to the risk of recurrence. We present the case of a young man admitted to our hospital for intermittent fever. The microbiologic investigations did not show any causative germ. We discovered a right ventricle thrombus on echocardiography. We confirmed the diagnosis of pulmonary embolism on CT angiogram. The patient developed oral and genital ulcerations which were consistent with Behçet's syndrome. The thrombus had disappeared after treatment with anticoagulant, corticosteroid and immunosuppressors. Intracardiac thrombosis can reveal Behçet's disease. An exhaustive examination and close monitoring should be performed in order to reveal pathognomonic signs as soon as possible and to promptly start the appropriate treatment.

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M-mode, 2-D and Doppler echocardiographic study in 65 patients with Behçet's syndrome

Cited by 65 publications

References 5 publications

Cardiovascular Involvement in Behçet's Disease

Cardiovascular Involvement in Behçet's Disease

Cardiovascular Involvement in Behcet's Disease.

Intracardiac Thrombus in a Young Man: Don't Forget Behçet's Disease!

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