Lymphoma of bone, muscle, and skin: CT findings.

Malloy, Patricia; Fishman, Elliot K.; Magid, Donna

doi:10.2214/ajr.159.4.1529847

Cited by 58 publications

(23 citation statements)

References 2 publications

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“…The CT features are often nonspecific, as the mass may be homogenous and of low attenuation [10] or of similar attenuation to muscle [11]. Following intravenous contrast medium, the masses may have similar attenuation to the adjacent skeletal muscle [11] or show avid homogenous contrast enhancement [8].…”

Section: Discussionmentioning

confidence: 99%

Lymphoma presenting as a musculoskeletal soft tissue mass: MRI findings in 24 cases

2008

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The purpose was to describe the MRI morphological features and signal intensity (SI) characteristics of 24 histologically proven cases of musculoskeletal soft tissue lymphoma presenting clinically as a suspected primary soft tissue sarcoma. This was a retrospective review of clinical notes and MRI studies of 24 patients with a histologically confirmed diagnosis of lymphoma. All patients presented to a specialist orthopaedic oncology unit with a suspected primary soft tissue sarcoma. Features assessed included lesion size and morphology, location, extension across anatomical compartments and signal intensity characteristics. The lesions were predominantly poorly defined with peritumoral oedema in ten cases. All tumours were of intermediate T1W SI, while 85% of lesions also showed intermediate T2W SI. Almost all cases that were located just deep to the fascia showed subcutaneous extension, while 50% had involvement of more than one muscle compartment. In 29% of cases, there was extension of tumour along the neurovascular bundle. Histo-pathologically, 23 lesions were non-Hodgkin's B-cell lymphoma. The MRI features of primary musculoskeletal soft tissue lymphoma include a mass with intermediate SI on T1W and T2W images, involvement of more than one anatomical compartment, subcutaneous extension and extension along the neurovascular bundle.

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Section: Discussionmentioning

confidence: 99%

Lymphoma presenting as a musculoskeletal soft tissue mass: MRI findings in 24 cases

2008

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“…It may present as a focal mass or diffuse muscular infiltration [ 28 ] . Ultrasonography features are non-specific and it appear as a heterogeneous, hypoechoic solid mass with irregular or poorly defined margins [ 26 ] .…”

Section: Muscular Diseasementioning

confidence: 99%

Imaging of musculoskeletal lymphoma

Lim¹,

Ong²

2013

Cancer Imaging

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Lymphoma of the musculoskeletal system involving the bone, muscle or skin is commonly due to secondary involvement from disseminated disease but can occasionally present as primary extranodal disease. Although radiological features are traditionally known to be non-specific, recognition of certain characteristics using summation of imaging modalities as well as knowledge of clinical features can help in making the diagnosis. Imaging also plays an integral role in treatment response assessments, especially via positron emission tomography/computed tomography functional imaging.

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“…PBL is defined as lymphoma that is confined to the bone or bone marrow without evidence of concurrent systemic involvement, and it has the best prognosis of all primary bone malignant lesions [12]. PBL is commonly found in the appendicular skeleton, typically affecting the metadiaphysis of the femur, tibia, and humerus, and it has a better prognosis than disseminated disease with secondary osseous involvement [11].…”

Section: Discussionmentioning

confidence: 99%

Distal appendicular skeletal involvement of diffuse large B-cell lymphoma on technetium-99m methylenediphosphonate bone scintigraphy and 18F-fluorodeoxyglucose positron emission tomography/computed tomography: a case report

Park

Kang

2017

J Med Case Reports

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BackgroundWe report a case of a patient with appendicular bone involvement of diffuse large B-cell lymphoma visualized by whole-body technetium-99m methylenediphosphonate bone scintigraphy (bone scan) and 18F-fluorodeoxyglucose positron emission tomography/computed tomography.Case presentationA 73-year-old Asian man who had gingival swelling of the labial area of the left maxillary lateral incisor presented to our institution. Positron emission tomography/computed tomography demonstrated hypermetabolic lesions with maximum standardized uptake values of 12.15 in the left testis, 1.92 in the skin of the right chest, and 2.88 in the left ulna and third metatarsal bone. A bone scan showed multiple uptakes in the left ulna, hand, both tibiae, and the left foot. We diagnosed the tumor as diffuse large B-cell lymphoma by excision. Magnetic resonance imaging showed enhanced signaling of lesions with soft tissue edema in the olecranon of the left ulna, the third metacarpal bone of the left hand, and the third metatarsal bone of the left foot. Magnetic resonance imaging findings prompted a diagnosis of lymphoma. Eight cycles of chemotherapy plus external radiotherapy targeted to the involved bone sites were given for 5 months. Follow-up positron emission tomography/computed tomography and bone scanning revealed the disappearance of hypermetabolism and decreased uptake in lesions compared with the previous images. Laboratory data were also all within the normal limits after chemotherapy.ConclusionsThis report highlights that appendicular bone involvement of diffuse large B-cell lymphoma can be detected on whole-body bone scans and by positron emission tomography/computed tomography.

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Lymphoma of bone, muscle, and skin: CT findings.

Cited by 58 publications

References 2 publications

Lymphoma presenting as a musculoskeletal soft tissue mass: MRI findings in 24 cases

Lymphoma presenting as a musculoskeletal soft tissue mass: MRI findings in 24 cases

Imaging of musculoskeletal lymphoma

Distal appendicular skeletal involvement of diffuse large B-cell lymphoma on technetium-99m methylenediphosphonate bone scintigraphy and 18F-fluorodeoxyglucose positron emission tomography/computed tomography: a case report

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